Buch, Englisch, 546 Seiten, HC gerader Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 1004 g
Basic Science and Clinical Concepts
Buch, Englisch, 546 Seiten, HC gerader Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 1004 g
ISBN: 978-0-387-77235-6
Verlag: Springer
We do not wish this book to compete with the other larger books in the Endocrine and Endocrine Surgery literature. In addition, it is not expected to cover benign adrenal diseases that have been covered in detail in other venues. We envision this book to be a very specialized and exhaustive text on basic, translational and clinical aspects of adrenal cancer.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Preface
1. History of ACC Research and Clinical Care
1.1. ACC - A 50 year retrospective view
1.2. History of ACC Treatment – A Surgical Perspective
2. Epidemiology, Presentation and Diagnosis
2.1. Epidemiology
2.2. Presentation and Diagnosis
2.3. Approach to the Adrenal incidentaloma
3.0. Imaging
3.1. Anatomic imaging
3.2. Functional imaging
4. Pathology
4.1. ACC Histopathology
4.2. Molecular and Cellular Pathology
5. Genetic & Molecular Aspects of ACC
5.1. Overview of the Genetics of ACC
5.2. Li Fraumeni Syndrome
5.3. P53 Molecular Genetics
5.4. Telomeres and ACC
5.5. Beckwith Wiedemann Syndrome
5.6. Insulin-like growth Factors
5.7. Wnt signaling
6. Models of Adrenocortical Cancer
6.1. Cellular origin and identity of ACC
6.2. Adrenocortical cell lines
6.3. Mouse Models of Adrenal Tumorigenesis
7. Therapies
7.1. Introduction
7.2. Mitotane
7.3. Cytotoxic Chemotherapy
7.4. Steroidogenesis and Therapy of Hormone Excess
7.5. Surgical therapy
7.6. Radiation Therapy
7.7. Surveillance and follow up of ACC
8 Unique ACC Cohorts and Future Perspectives
8.1. Aldosterone producing ACC
8.2. Childhood ACC
8.3. Molecular Profiling of Adrenal Cancer
8.4. Clinical Registries: Dutch and European experiences
8.5. Emerging Strategies