Formulation and Development of Ophthalmic Solution

Formulation and Development of Ophthalmic Solution for Non-steroidal Anti-inflammatory Drug (NSAID)

ISBN: 978-3-659-26823-6
Verlag: LAP Lambert Academic Publishing

Buch, Englisch, 128 Seiten, Format (B × H): 150 mm x 220 mm

Ketorolac tromethmaine is a Nonsteroidal anti-inflammatory drug. It is used as Antipyretic, anti-inflammatory and analgesic. It is indicated Ketorolac tromethamine ophthalmic solution is indicated for the temporary relief of ocular itching due to seasonal allergic conjunctivitis & for the treatment of postoperative inflammation. Preservative in high concentration hazardous to Ocular cell. Therefore, the aim of the present study was to formulate a formulation for ketorolac tromethmine (0.5%) ophthalmic solution using different concentration of Benzalkonium chloride as preservative. While reducing the concentration of Benzalkonium chloride it must be keep in mind that added quantity of preservative must meet compendial requirement of Preservative Efficacy Testing as per United state Pharmacopoeia (USP).The present research work is also planned to provide the data about the selection of suitable primary packaging material for Ketorolac tromethmine (0.5%) to achieve the better stability during the shelf life of the product.

Autoren/Hrsg.

Bhople, Amit

Sheaikh, Sameer

Patange, Harish

Über Autor(innen)

Mr. Amit Bhople has obtained his post graduation i.e. M.Pharm with specialization in Pharmaceutics. His main area of research is Novel Drug Delivery System and Osmotically controlled drug delivery system. He published number of research of research papers in various journals of national and international repute.