Pediatric Nephrology

8th Auflage 2022
ISBN: 978-3-030-52720-4
Verlag: Springer

Medienkombination, Englisch, 2500 Seiten, Buch mit Online-Zugang, Format (B × H): 155 mm x 235 mm

Over the course of the previous seven editions, Pediatric Nephrology has become the standard reference text for students, trainees, practicing physicians (pediatricians, nephrologists, internists, and urologists), subspecialists, and allied health professionals seeking information about children’s kidney diseases. It is global in perspective, reflecting the fact that the international group of editors are all acknowledged world experts.

The latest edition of this text is no different, providing a comprehensive, state-of-the-art overview on pediatric nephrology. Much like the previous edition, the latest edition reviews the most critical aspects of the field. Topics covered include developmental physiology and diseases, renal physiology and diagnostic approaches, glomerular disease, kidney involvement in systemic diseases, renal tubular disorders, homeostasis, cystic kidney disease and related disorders, urinary tract disorders, hypertension, acute kidney injury, and chronic kidney failure.

Unlike the previous edition, however, the chapters in this edition now combine physiology, clinical management, and pathology for ease of use. The latest edition also includes a new section on the evaluation of different disorders that can have multiple etiologies, setting the stage for the evaluation and management of specific diseases.

This book serves as a superb resource and an invaluable asset for practitioners, health professionals, and trainees seeking out information about children's kidney diseases.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Emma, Francesco

Goldstein, Stuart L.

Bagga, Arvind

Bates, Carlton M.

Shroff, Rukshana

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Pädiatrie, Neonatologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Allgemeinmedizin, Familienmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Nephrologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Urologie, Andrologie, Venerologie

Inhaltsverzeichnis

I Developmental Physiology and Diseases
1. Pre-natal development of the kidneys and urinary tract2. Post-natal renal maturation3. Congenital abnormalities of the kidneys and the urinary tract4. Stem cells and kidney regeneration
II Renal Physiology and Diagnostic Approaches
5. Assessment of kidney function6. Imaging kidneys and the urinary tract 7. Technical aspects of renal pathology8. Approach to the child with hematuria and/or proteinuria
III Glomerular Diseases
9. Nephrotic syndrome: classification and evaluation10. Genetic bases of nephrotic syndrome11. Congenital nephrotic syndrome12. Clinical aspects of genetic forms of nephrotic syndrome13. Inherited diseases of the glomerular basement membrane14. Steroid sensitive nephrotic syndrome15. Non-genetic forms of steroid resistant nephrotic syndrome16. Membranous nephropathy
IV Kidney Involvement in Systemic Diseases
17. Evaluation of children with nephritic syndrome18. IgA Nephropathy19. Henoch Schönlein Purpura Nephritis20. Renal vasculitis 21. Lupus nephritis22. Autoantibodies and kidney diseases23. C3 glomerulopathies24. Atypical HUS and TTP25. Infection-related HUS26. Acute post-streptococcus glomerulonephritis27. Infections that affect the kidney (non-viral)28. Viral infections and the kidney29. The kidney in sickle cell disease30. The kidney in type I diabetes31. The kidney in metabolic syndrome32. Renal Manifestations of Metabolic Disorders33. The kidney in methyl malonic acidemia34. The kidney in mitochondrial cytopathies35. Fabry disease36. Primary hyperoxaluria
V Renal Tubular Disorders
37. Fanconi Syndrome38. Cystinosis39. Aminoaciduria and Glycosuria40. Renal hypophosphatemia41. Inherited disorders of sodium and potassium handling42. Inherited disorders of renal magnesium handling 43. Inherited disorders of renal calcium handling 44. Renal Tubular Acidosis45. Inherited disorders of water handling46. Tubulointerstitial nephritis
VI Homeostasis
47. Sodium and Water Disorders: evaluation and management48. Potassium disorders: evaluation and management49. Clinical use of diuretics
VII Cystic Kidney Diseases and Related Disorders
50. Autosomal Dominant Polycystic Kidney Diseases51. Autosomal Recessive Polycystic Kidney Diseases52. Renal involvement in tuberous sclerosis53. Nephronophtisis and other ciliopathies54. Autosomal Dominant Tubulointerstitial Kidney Diseases
VIII Urinary Tract Disorders
55. Urolithiasis and nephrocalcinosis56. Urinary tract infections57. Vesicoureteral reflux58. Obstructive uropathies59. Bladder disorders60. Enuresis61. Pediatric renal tumors62. Onconephrology
IX Hypertension
63. Pathophysiology and epidemiology of hypertension in children64. Evaluation and management of hypertension65. Renovascular hypertension: evaluation and management
X Acute Kidney Injury
66. Pathogenesis of acute kidney injury67. Evaluation and management of acute kidney injury in neonates68. Evaluation and management of acute kidney injury in children69. Nephrotoxins
XI Chronic Kidney Failure
70. Progression of chronic kidney disease and nephroprotection71. Epidemiology and management of Chronic Kidney Disease72. Nutrition, Growth and Development73. CKD-MBD74. Anemia in CKD75. Assessment of volume status in CKD76. Peritoneal Dialysis77. Hemodialysis78. Infant dialysis79. Adequacy of dialysis80. Renal Transplantation: Evaluation of children and donors81. Renal transplantation: surgical and perioperative management82. Renal transplantation: immunosuppression83. Renal transplantation: disease recurrence84. Renal transplantation: infectious complications85. Renal transplantation: non- infectious complications and long-term outcome86. Multi-organ transplants and the kidney in other solid organ transplantation87. Ethical issues in pediatric nephrology88. Drug dosing in abnormal kidney functions in Children with Abnormal Renal Function
XII Addendum
89. Normal reference values

Über Autor(innen)

Francesco Emma, MDBambino Gesù Children’s Hospital – IRCCSDivision of NephrologyRome, Italy
Stuart L. Goldstein, MDDirector, Center for Acute Care Nephrology Medical Director, Pheresis ServiceCo-Director, Heart Institute Research CoreCincinnati Children's Hospital Medical CenterDivision of Nephrology and HypertensionCincinnati, OHUSA
Arvind Bagga, MDAll India Institute of Medical SciencesIndian Council of Medical Research Advanced Center for Research in NephrologyDivision of NephrologyAnsari Nagar East, New DelhiIndia
Carlton M. Bates, MDChief, Division of Pediatric NephrologyChildren’s Hospital of Pittsburgh University of Pittsburgh Medical CenterrPittsburgh, PAUSA
Rukshana Shroff, MD, FRCPCH, PhDGreat Ormond Street Hospital for ChildrenNHS Foundation TrustLondon, UK
Dr. Emma received his Medical Degree and specialized in Pediatrics from the Catholic University of Louvain, Brussels, Belgium. He then completed his training in Pediatric Nephrology at Boston Children's Hospital, Harvard Medical School. In 1998, Dr. Emma moved to the Bambino Gesù Children's Hospital - IRCCS, in Rome, where he has set-up the Nephrology Research Laboratory and was appointed Chief of the Division of Pediatric Nephrology in 2005. He currently holds the position of Head of the Department of Pediatric Subspecialties.
Dr. Emma has authored more than 160 research articles in peer-reviewed journals and is the author of several textbook chapters and one of the editors of the Pediatric Nephrology textbook. He is the chair of the ESPN (European Society of Pediatric Nephrology) Working Group on Inherited Renal Disorders. His primary research interests are in rare renal diseases, in particular cystinosis and idiopathic nephrotic syndrome.
Stuart L. Goldstein, MD, has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000. Dr. Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population. Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 52 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI.
Carl Bates, MD, has had a career as a clinical pediatric nephrologist and basic research scientist for over 15 years. Dr. Bates was recruited to Children’s Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine in 2008, where he is currently Professor of Pediatrics, Cell Biology and Developmental Biology; Vice Chair of Basic Research in Pediatrics, Division Chief of Pediatric Nephrology; and co-Director of the Pediatric Nephrology Fellowship Training Program.
In addition to caring for children with pediatric kidney disease for many years, Dr. Bates has had an internationally-recognized research program focused on genetic regulation of kidney and bladder development, with more than 15 years of continuous funding by the National Institutes of Health. His mouse models of kidney and bladder disease have helped us understand many of the structural kidney and bladder birth defects seen in children, which make up the most frequent causes of kidney disease in children.
Dr. Shroff is a Consultant Pediatric Nephrologist at Great Ormond Street Hospital and looks after children with chronic kidney disease (CKD) and those on dialysis.
Dr. Shroff’s PhD and current research focus on cardiovascular disease in children with CKD, with particular emphasis on identifying and reducing the burden of modifiable risk factors in dialysis patients. She has supervised 3 MSc students and currently co-supervises 2 PhD students.
She says "I hope that my approach through ‘translational’ (bench-to-bedside) research will improve the lives of dialysis patients by reducing their risks of heart disease and bone problems".
She has published widely in her field and written educational reviews and book chapters.
Dr. Shroff is an associate editor for Pediatric Nephrology, the main journal in the field.