García-Segura Hormones and Brain Plasticity
Buch, Englisch, Reihe: Oxford Series in Behavioral Ne
Band: 1
496 Seiten, Gebunden, Format (B × H): 163 mm x 236 mm, Gewicht: 839 g
Erscheinungsjahr 2009,
Band: 1, 496 Seiten, Gebunden, Format (B × H): 163 mm x 236 mm, Gewicht: 839 g
Reihe: Oxford Series in Behavioral Ne
ISBN: 978-0-19-532661-1
Verlag: OXFORD UNIV PR
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entire life of the organism.
Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic activity of the brain to the incessant modifications in external and internal environments. Their regulation of neuroplastic events in a given moment predetermines new neuroplastic responses that will occur in the future, adapting brain reorganization to changing physiological and behavioral demands throughout the life of the organism. The cross-regulation of brain plasticity and hormones
integrates information originated in multiple endocrine glands and body organs with information coming from the external world in conjunction with the previous history of the organism. Multiple hormonal signals act in concert to regulate the generation of morphological and functional changes in neural
cells, as well as the replacement of neurons, glial, and endothelial cells in neural networks. Brain remodeling, in turn, is involved in controlling the activity of the endocrine glands and regulating hormonal secretions. This bidirectional adjustment of brain plasticity in response to hormonal inputs, and adjustment of hormonal concentrations in response to neuroplastic events are crucial for maintaining the stability of the inner milieu and for the generation of adequate behavioral responses
in anticipation of—and in adaptation to—new social and environmental circumstances and life events, including pathological conditions.
Garcia-Segura, Luis Miguel
Luis M. Garcia-Segura is Research Professor and head of the department of functional and systems neurobiology at the Cajal Institute of the Spanish National Research Council (CSIC) in Madrid. He is internationally recognized by his pioneering studies on the actions of hormones in the regulation of brain plasticity.
entire life of the organism.
Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic activity of the brain to the incessant modifications in external and internal environments. Their regulation of neuroplastic events in a given moment predetermines new neuroplastic responses that will occur in the future, adapting brain reorganization to changing physiological and behavioral demands throughout the life of the organism. The cross-regulation of brain plasticity and hormones
integrates information originated in multiple endocrine glands and body organs with information coming from the external world in conjunction with the previous history of the organism. Multiple hormonal signals act in concert to regulate the generation of morphological and functional changes in neural
cells, as well as the replacement of neurons, glial, and endothelial cells in neural networks. Brain remodeling, in turn, is involved in controlling the activity of the endocrine glands and regulating hormonal secretions. This bidirectional adjustment of brain plasticity in response to hormonal inputs, and adjustment of hormonal concentrations in response to neuroplastic events are crucial for maintaining the stability of the inner milieu and for the generation of adequate behavioral responses
in anticipation of—and in adaptation to—new social and environmental circumstances and life events, including pathological conditions.
Garcia-Segura, Luis Miguel
Luis M. Garcia-Segura is Research Professor and head of the department of functional and systems neurobiology at the Cajal Institute of the Spanish National Research Council (CSIC) in Madrid. He is internationally recognized by his pioneering studies on the actions of hormones in the regulation of brain plasticity.
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