Torbett / Goodsell / Richman | The Future of HIV-1 Therapeutics | Buch |

Torbett / Goodsell / Richman The Future of HIV-1 Therapeutics

Resistance Is Futile?

Softcover Nachdruck of the original 1. Auflage 2015, Band: 389, 254 Seiten, Kartoniert, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 4044 g Reihe: Current Topics in Microbiology and Immunology
ISBN: 978-3-319-37450-5
Verlag: Springer, Berlin

Torbett / Goodsell / Richman The Future of HIV-1 Therapeutics

This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.



Weitere Infos & Material

HIV Therapy Looking Towards the FutureDavid Looney, Ariel Ma, and Scott Johns Computational challenges of structure-based approaches applied to HIVStefano Forli and Arthur J. Olson Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1Mattia Mori, Lesia Kovalenko, Sébastien Lyonnais, Danny Antaki, Bruce E. Torbett, Maurizio Botta, Gilles Mirambeau, and Yves Mély HIV-1 integrase multimerization as a therapeutic targetLei Feng, Ross Larue, Jacques J. Kessl, and Mamuka Kvaratskhelia Targeting HIV transcription: The quest for a functional cureGuillaume Mousseau, Sonia Mediouni, and Susana T. Valente Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer LadderStuart F.J. Le Grice HIV-1 Gag: An Emerging Target for Antiretroviral TherapyPhilip R. Tedbury and Eric O. Freed The Triple Threat of HIV-1 Protease InhibitorsMarc Potempa, Sook-Kyung Lee, Richard Wolfenden, and Ronald Swanstrom Illustrations of the HIV Life CycleDavid S. Goodsell


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