Green Synthetic Approaches for Biologically Relevant Heterocycles

Erscheinungsjahr 2014
ISBN: 978-0-12-800070-0
Verlag: Elsevier Health Sciences

Buch, Englisch, 632 Seiten, Format (B × H): 215 mm x 276 mm, Gewicht: 1990 g

Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry.

Zielgruppe

<p>Chemists (synthetic, medicinal, natural products, combinatorial); pharmacologists; biochemists; researchers in drug discovery and agrochemical industries; advanced and research students in these areas</p>

Autoren/Hrsg.

Brahmachari, Goutam

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie Umweltchemie, Lebensmittelchemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Agrarwissenschaften Ackerbaukunde, Pflanzenbau

Inhaltsverzeichnis

1. Green synthetic approaches for biologically relevant heterocycles: An overview 2. Synthesis of bioactive five- and six-membered heterocycles catalyzed by heterogeneous supported metals 3. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes 4. Metal-catalyzed routes for the synthesis of furocoumarins and coumestans 5. Green solvents for eco-friendly synthesis of bioactive heterocyclic compounds 6. Green catalytic synthesis of heterocyclic structures using carbon dioxide and related motifs 7. Synthetic approaches to small and medium size aza-heterocycles in aqueous media 8. Green synthetic approaches for biologically relevant 2-amino-4H-pyrans and 2-amino-4H-pyran-annulated heterocycles in aqueous media 9. Sustainable synthesis of benzimidazoles, quinoxalines and congeners 10. Green and catalytic methods for ?-lactone synthesis 11. Green synthetic approaches for medium ring-sized heterocycles of biological interest 12. Organocatalyzed Biginelli reactions: A greener chemical approach for the synthesis of biologically active 3,4-dihydropyrimidin-2(1H)-ones/-thiones 13. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest 14. Organo hypervalent iodine reagents in the synthesis of bioactive heterocycles 15. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds 16. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles 17. Ionic liquids prompted synthesis of biologically relevant five and six-membered heterocyclic skeletons: An update 18. Heterocycles-based ionic liquid-supported synthesis of small organic molecules 19. Microwave-induced synthesis of heterocycles of medicinal interests 20. Application of microwave irradiation in the synthesis of P-heterocycles 21. Use of ultrasound in the synthesis of heterocycles of medicinal interest

Über Autor(innen)

Brahmachari, Goutam
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992 with a specialization in organic chemistry. After that, receiving his Ph.D. in 1997 in chemistry from the same university, he joined his alma mater the very next year and currently holds the position of a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include natural products chemistry, synthetic organic chemistry, green chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With about 23 years of experience in teaching and research, he has produced 235 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 26 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves as a life member for the Indian Association for the Cultivation of Science (IACS), Indian Science Congress Association (ISCA), Kolkata, and Chemical Research Society of India (CRSI), Bangalore. He has also been serving as an associate editor for Current Green Chemistry. Prof. Brahmachari serves as the founder series editor of Elsevier Book Series' Natural Product Drug Discovery. He is an elected fellow of the Royal Society of Chemistry, and a recipient of CRSI (Chemical Research Society of India) Bronze Medal, 2021 (contributions to research in chemistry), INSA (Indian National Science Academy) Teachers Award, 2019, Dr. Kalam Best Teaching Faculty Award, 2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World's Top 2% Scientists (organic chemistry category) in 2020 and 2021 and the AD Scientific Index 2022 World Ranking of Scientists, 2022.