Endogenous Opioids

From Basic Science to Biopsychosocial Applications
1. Auflage 2024
ISBN: 978-3-031-45492-9
Verlag: Springer International Publishing

Buch, Englisch, 455 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 861 g

Reihe: Advances in Neurobiology

This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus. Topics covered range from basic scientific investigations, to clinical applications, to investigations in areas such as oncology, childbirth, and disordered eating, to psychosocial contexts such as volunteering and positive emotions. One of the main goals of Endogenous Opioids is to provide recommendations for new directions in medical research and health policy that are rooted in sound scientific research.

Zielgruppe

Research

Autoren/Hrsg.

Kerr, Patrick L.

Sirbu, Cristian

Gregg, John M.

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Preface                                                                                                                                  

Chapter 1: Introduction to the volume: The Journey Ahead                                         

                        Patrick L. Kerr, Cristian Sirbu, and John Gregg

Chapter 2: The Foundational Science of Endogenous Opioids and Their Receptors        

                        Simona Tache, Patrick L. Kerr, and Cristian Sirbu

Chapter 3: Interactions Between Endogenous Opioids and the Immune system         

                        Wei Du

Chapter 4: The Opioid Growth Factor in Growth Regulation                                                            and Immune Responses in Cancer

                        Gerald R. Hankins and Robert T. Harris

Chapter 5:Role of Endorphins in Breast Cancer Pathogenesis and Recovery                   

                        David H. Nguyen

Chapter 6: Modulatory Processes in Craniofacial Pain States                                               

                        Barry J. Sessle

Chapter 7: Enkephalin Rescues Temporomandibular Joint                                           

                   Pain Related Behavior in Rats

                        Karin N. Westlund  and A. Caitlynn Iddings

Chapter 8: Endogenous Opioids and Exercise-Related Hypoalgesia:                                     

                   Modern Models, Measurement, and Mechanisms of Action

Allan H.Goldfarb, Robert R. Kraemer, and Brandon A. Baiamonte

Chapter 9: Pain, Fear, Anxiety, and Stress: Relation to                                                   

                    the Endogenous Opioid System

                        Nicholas J. Felicione, Melissa D. Blank, Casey D. Wright,

                        and Daniel W. McNeil

Chapter 10: The Roles of Endogenous Opioids in Placebo and Nocebo Effects:         

                      From Pain to Performance to Prozac

                        Patrick L. Kerr and John M. Gregg

Chapter 11: Physical Exercise as an Intervention for Depression: Evidence for 

                        Efficacy and Mu-Opioid Receptors as a Mechanism of Action

                        Colleen PettreyPatrick L. Kerr, and T.O. Dickey

Chapter 12: The Endogenous Opioid System as a Pathway of Positive Emotions      

                        Jennifer Barenz, Maeve O’Donnell, and Joey Smith

Chapter 13: Endogenous Opioids and Volunteering:                                                                             On the Evolutionary Significance of Helping Others

                        Alina Simona Rusu, Ph.D.

Chapter 14: Endogenous and Exogenous Opioids: Role in                                              

                      Substance Use Disorders

                        Lindsay Acree, Pharm.D., AE-C

Chapter 15: Endogenous Opioid Activity as the Mechanism of Action for                   

                      Mitragyna Speciosa (Kratom): The Current State of the Evidence

                        Adina Bowe and Patrick L. Kerr

Chapter 16: Endogenous Opioids in the Homeostatic Regulation                                

                      of Hunger, Satiety, and Hedonic Eating: Neurobiological Foundations

                        Marcela Rodriguez Flores and Sylvana Stephano Zúñiga

Chapter 17: Role of Endogenous Opioids in the Pathophysiology                                          

                       of Obesity and Eating Disorders

                        Sylvana Stephano Zuniga, Marcela Rodriguez Flores, and Adriana Albu

Chapter 18: Integration of Endogenous Opioid System Research                                     

                      in the Interprofessional  Diagnosis and Treatment of Obesity

                      and Eating Disorders

                        Marcela Rodriguez Flores and Sylvana Stephano Zuniga

Chapter 19: The Role of Endogenous Opioids in Cardioprotection                                    

                        Cristina Sirbu, M.D.

Chapter 20: Endorphins, Sexuality, and Reproduction                                                   

                        Marjan Khajehei, PhD MSc, BSc, RM

Chapter 21: Depression, Cancer, Inflammation, and Endogenous Opioids:                     

                      Pathogenic Relationships and Therapeutic Options           

                        Jennifer Hancock, Cristian Sirbu, and Patrick L. Kerr

Über Autor(innen)

Dr. Patrick Kerr completed his Master’s and doctoral degrees in clinical psychology at the University of North Dakota. He completed his pre-doctoral internship training at the West Virginia University School of Medicine-Charleston campus and Charleston Area Medical Center. Dr. Kerr is a clinical psychologist, specializing in the treatment of severe psychopathology, suicidality, and traumatic stress. He is currently an Associate Professor in the Department of Behavioral Medicine and Psychiatry at West Virginia University School of Medicine-Charleston. He serves as Director of the WVU Behavioral Science and Psychopathology Research Division, and as Director of the WVU Dialectical Behavior Therapy Services Program.

His main lines of research and academic work emphasize common mechanisms of severe psychiatric disorders, emotion regulation, suicide risk, trauma, and the psychobiological mechanisms of psychopathology.

Dr. Cristian Sirbu is a Clinical Associate Professor at West Virginia University School of Medicine-Charleston campus and Charleston Area Medical Center (CAMC) and a Research Scientist at the CAMC Center for Cancer Research. He completed his dental and psychology doctoral degrees in Romania and a clinical psychology doctoral degree at Marshall University.

His scholarly and clinical work are focused on assessment and treatment of anxiety, mood disorders and chronic pain across multiple populations and the enhancement of psychosocial interventions using pharmacological and technology-based approaches. He is interested in immunological mechanisms of psychopathology and the implementation of Patient-Reported Outcomes in oncology. 

Dr. John Gregg is a retired oral and maxillofacial surgeon and who served in academic positions at multiple institutions during his career. Dr. Gregg’s academic career has included appointments as Professor of Surgery at University of North Carolina, Virginia Tech University, and Virginia Commonwealth University. During his academic and professional training, he completed five degrees as well as clinical residency in Oral and Maxillofacial surgery at the University of Michigan.   

Dr. Gregg’s preclinical research was the first to demonstrate that peripheral injury of rodent trigeminal nerves may produce neuroanatomic pathoses in the transganglionic and central spinal trigeminal complex. He continues his active program of clinical research post-retirement, with an emphasis on mechanisms of neuropathic pain and microsurgical management of trigeminal nerve injuries.