Pasteurella multocida

Molecular Biology, Toxins and Infection
2012
ISBN: 978-3-642-31016-4
Verlag: Springer

Buch, Englisch, Band 361, 150 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 412 g

Reihe: Current Topics in Microbiology and Immunology

It is more than 125 years since Louis Pasteur identified as the causative agent of “choléra des poules” the bacterium that now bears his name. Since that time, Pasteurella multocida has been recognized as the causative agent of a wide range of infections in a wide range of animal species as well as in humans. Indeed, the species name multocida could be literally translated as “multi-killer”. The term pasteurellosis is now widely applied to describe infections of mammals and birds caused by P. multocida. It is therefore surprising that a detailed knowledge of the cellular and molecular basis for pathogenesis in pasteurellosis lags behind what has been elucidated for many other bacterial species. In particular, the molecular basis for host predilection remains completely unknown.

This volume brings together contributions from experts in the field of Pasteurella research. It covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of Pasteurella multocida toxin and its interaction with host tissues, cells, immune system, and signalling pathways.

Zielgruppe

Research

Autoren/Hrsg.

Aktories, Klaus

Adler, Ben

Orth, Joachim H.C.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie

Inhaltsverzeichnis

Preface.- Chapter 1 I.W. Wilkie, M. Harper, John D. Boyce, and B. Adler: Pasteurella multocida: Diseases and Pathogenesis.- Chapter 2 John D. Boyce, Torsten Seeman, Ben Adler, and Marina Harper: Pathogenomics of Pasteurella multocida.- Chapter 3 Marina Harper, John D. Boyce and Ben Adler: The Key Surface Components of Pasteurella multocida: Capsule and Lipopolysaccharide.- Chapter 4 Katharina Kubatzky: Pasteurella multocida and immune cells.- Chapter 5 Joachim H.C. Orth and Klaus Aktories: Molecular biology of Pasteurella multocida toxin.- Chapter 6 Brenda A. Wilson and Mengfei Ho: Pasteurella multocida toxin interaction with host cells: entry and cellular effects.- Chapter 7 Yasuhiko Horiguchi: Swine atrophic rhinitis caused by Pasteurella multocida toxin and Bordetella dermonecrotic toxin.- Chapter 8 Alistair Lax: The Pasteurella multocida toxin – a new paradigm for the link between bacterial infection and cancer.- Subject index