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PTSD

Brain Mechanisms and Clinical Implications

  • Book
  • © 2006

Overview

Editors:
  1. Nobumasa Kato

    1. Department of Neuropsychiatry, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

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  2. Mitsuhiro Kawata

    1. Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan

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    You can also search for this editor in PubMed   Google Scholar

  3. Roger K. Pitman

    1. Harvard Medical School, Massachusetts General Hospital, Charlestown, USA

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  • Unique to explain neurological mechanisms of PTSD, and then expand to the current clinical implications

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Table of contents (24 chapters)

  1. Front Matter

    Pages I-XI
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  2. Basic Mechanism of PTSD and Stress-Related Brain Dysfunctions

    1. Front Matter

      Pages 1-1
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    2. Neuroanatomical and Molecular Changes in Stress Responses During Early Life: Implications for Stress Disorders

      • Toru Nishikawa, Akeo Kurumaji, Takashi Ito, Asami Umino, Sumikazu Ishii
      Pages 3-11

    3. Cortisol and PTSD: Animal Experiments and Clinical Perspectives

      • E. Ronald de Kloet, Melly S. Oitzl
      Pages 13-27

    4. Stress and Corticosteroid Receptors

      • Mitsuhiro Kawata, Mayumi Nishi, Ken-ichi Matsuda, Hirotaka Sakamoto, Cui Honghai, Takanori Yoshii
      Pages 29-36

    5. Stress Vulnerability Induced by Neonatal Isolation and the Disturbance Between the Phosphorylation and Dephosphorylation of CREB

      • Shigeru Morinobu, Seiichi Tsuji, Michihiro Takahashi, David S. Russell, Jun Takahashi, Kazuhide Tanaka et al.
      Pages 37-45

    6. Neuroscience of Emotional Memory and Posttraumatic Stress Disorder

      • Shigenobu Kanba, Koutaro Kudo, Naoko Kaneko, Henny Wati, Hironobu Iguchi, Keiko Takemoto
      Pages 47-53

    7. Studies on Pathophysiology of PTSD Using the SPS Model

      • Kazuhisa Kohda, Kunio Kato, Nobumasa Kato
      Pages 55-59

    8. Mechanisms of Lasting Change in Anxiety Induced by Severe Stress

      • Robert Adamec, Jacqueline Blundell, Kirby Strasser, Paul Burton
      Pages 61-81

    9. Altered Emotional Behaviors in Mammalian Bombesin Receptor Knockout Mice: Implication for the Molecular Pathogenesis of Stress-Induced Psychiatric Disorders in Humans

      • Keiji Wada, Kazuyuki Yamada, Yuko Santo-Yamada, Hiroshi Maeno, Etsuko Wada, Masayuki Sekiguchi
      Pages 83-88

    10. Role of Stress Hormones and the Amygdala in Creating Lasting Memories

      • James L. McGaugh, Benno Roozendaal, Shoki Okuda
      Pages 89-103

    11. Drug Discovery for PTSD: Characterization of an Animal Model of PTSD and PET Imaging of Brain Glucocorticoid Receptor

      • Katsuya Harada, Takahiro Matsuya, Takayuki Yamaji, Yoshihiro Murakami, Akihiro Noda, Hiroyuki Takamatsu et al.
      Pages 105-111

    12. Tissue Metabolism of Glucocorticoids: New Controls of Cognitive Function and the Stress Response

      • Jonathan R. Seckl
      Pages 113-135

    13. Maternal Deprivation in Neonatal Period and Biological Rhythms

      • Ken-ichi Honma, Ayano Yamazaki, Yoshio Ootsuki, Natsumi Noda, Sato Honma
      Pages 137-144

  3. Clinical Implications for PTSD and Perspectives in Psychiatry

    1. Front Matter

      Pages 145-145
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    2. Current Perspectives on Clinical Studies of PTSD in Japan

      • Yoshiharu Kim
      Pages 147-154

    3. Psychosocial and Genetic Susceptibility to Posttraumatic Stress Disorder

      • Min-Soo Lee, Heon-Jeong Lee
      Pages 155-167

    4. Intrusion in Women with Breast Cancer

      • Yutaka Matsuoka, Mitsue Nagamine, Yosuke Uchitomi
      Pages 169-178

    5. Earthquake-Related PTSD: A Follow-up Study in Prevalence, Comorbidity, Quality of Life, and Biological Correlates

      • Tung-Ping Su, Frank Huang-Chih Chou, Wen-Chen Ou-Yang, Pesus Chou
      Pages 179-191

    6. Psychological Consequences for Students Who Survived the Ehime Maru Accident: A 26-Month Follow-Up Study

      • Masaharu Maeda, Takayuki Maruoka, Hisao Maeda
      Pages 193-202
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Keywords

About this book

Recent catastrophic events, such as the attack on the New York World Trade Center and the devastating tsunami in the Indian Ocean, have drawn increasing attention to post-traumatic stress disorder, or PTSD. Once thought of only in psychological terms, PTSD has emerged as the model mental disorder for studying the effect of the environment on human biological systems, especially the brain. This book breaks new ground by offering neuroscientific insights into PTSD and their implications for diagnosis, prevention, and treatment. The recent explosion of biological investigation into this distressing and disabling condition has been led by this volume’s authors, who range from skilled basic scientists to experienced diagnosticians and therapists. Their contributions epitomize state-of-the-art, translational research in clinical neuroscience, and will prove to be an invaluable source of reference for practitioners and researchers in this field.

Editors and Affiliations

  • Department of Neuropsychiatry, Faculty of Medicine, The University of Tokyo, Tokyo, Japan

    Nobumasa Kato

  • Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Mitsuhiro Kawata

  • Harvard Medical School, Massachusetts General Hospital, Charlestown, USA

    Roger K. Pitman

Bibliographic Information

  • Book Title: PTSD

  • Book Subtitle: Brain Mechanisms and Clinical Implications

  • Editors: Nobumasa Kato, Mitsuhiro Kawata, Roger K. Pitman

  • DOI: https://doi.org/10.1007/4-431-29567-4

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Tokyo 2006

  • Hardcover ISBN: 978-4-431-29566-2Published: 01 February 2006

  • Softcover ISBN: 978-4-431-56087-6Published: 23 October 2016

  • eBook ISBN: 978-4-431-29567-9Published: 03 July 2007

  • Edition Number: 1

  • Number of Pages: XI, 304

  • Number of Illustrations: 2 illustrations in colour

  • Topics: Neurobiology, Behavioral Sciences, Psychiatry, Psychopharmacology

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