Overview
- Covers all aspects of radiation myelopathy and all species in which it has been studied
- Examines the impacts of a wide range of factors
- Discusses dose-response modeling, treatment, and medicolegal issues
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Table of contents (9 chapters)
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Front Matter
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Back Matter
Keywords
About this book
This book covers every aspect of radiation myelopathy and considers the evidence from all species in which it has been studied. The historical and current understanding of the pathogenesis of this rare but devastating injury is first discussed. The evidence regarding the role of a variety of factors in radiation myelopathy is then reviewed. Readers will find detailed information on the impacts of total radiation dose, radiation volume, dose fractionation, hyper fractionation, age, anatomic level, comorbidities, radiation modifiers, other therapies, and retreatment of the spinal cord. Given the similarity of the pathogenesis of radiation myelopathy in humans and experimental animals, the potential for cross-species modelling of dose response is explored, with attention to relevant species differences. Treatment of the condition is also fully considered. New theories are presented regarding retreatment, small volume response, and the final step in white matter necrosis. The final chapter addresses the medicolegal issues elicited by radiation myelopathy, which is often the result of treatment error. Radiation Myelopathy will be of high value for radiation oncologists, radiation physicists, dosimetrists, biologists, neurologists, medical oncologists, and attorneys.
Authors and Affiliations
About the author
Timothy Schultheiss is a radiation physicist who has pursued a long career in the late effects of radiation on normal tissues. His interest in dose-response modelling arose from his research for his doctoral thesis on biological optimization of radiation dose distributions. Continuing a lifelong interest in dose and volume responses in normal tissues, his research in radiation myelopathy is particularly well known, covering both clinical and experimental arenas. Approximately 1800 of the more than 10000 citations of his published work reference his research on radiation myelopathy. Educated at Wake Forest and Brown Universities, Dr. Schultheiss has held faculty positions at University of Texas M.D. Anderson Cancer Centre, Fox Chase Cancer Centre, and City of Hope.
Bibliographic Information
Book Title: Radiation Myelopathy
Authors: Timothy Schultheiss
DOI: https://doi.org/10.1007/978-3-030-94658-6
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-94657-9Published: 01 July 2022
Softcover ISBN: 978-3-030-94660-9Published: 02 July 2023
eBook ISBN: 978-3-030-94658-6Published: 30 June 2022
Edition Number: 1
Number of Pages: XXVI, 240
Number of Illustrations: 29 b/w illustrations, 26 illustrations in colour
Topics: Radiotherapy, Effects of Radiation/Radiation Protection, Oncology, Medical and Radiation Physics