Slikker Jr / Paule / Wang | Handbook of Developmental Neurotoxicology | Buch | 978-0-12-809405-1 | sack.de

Buch, Englisch, 616 Seiten, Format (B × H): 284 mm x 227 mm, Gewicht: 1950 g

Slikker Jr / Paule / Wang

Handbook of Developmental Neurotoxicology

Buch, Englisch, 616 Seiten, Format (B × H): 284 mm x 227 mm, Gewicht: 1950 g

ISBN: 978-0-12-809405-1
Verlag: Elsevier Health Sciences


Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience.
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Weitere Infos & Material


PART I. CELLULAR AND MOLECULAR MORPHOGENESIS OF THE NERVOUS SYSTEM PART II. DEVELOPMENTAL NEUROBIOLOGY/TOXICOLOGY PART III. SYNAPTOGENESIS AND NEUROTRANSMISSION PART IV. NUTRIENT AND CHEMICAL DISPOSITION PART V. BEHAVIORAL ASSESSMENT PART VI. CLINICAL ASSESSMENT AND EPIDEMIOLOGY PART VII. SPECIFIC NEUROTOXIC SYNDROMES PART VIII. RISK ASSESSMENT


Paule, Merle G.
Dr. Paule received his B.S. in Biochemistry and his Ph.D. in Pharmacology and Toxicology at the University of California at Davis. In 1983 he began work at the FDA's National Center for Toxicological Research in Jefferson, Arkansas, where he remains today. He attained certification as one of FDA's Senior Biomedical Research Scientists in 2000 and in 2005 became the Director of the Division of Neurotoxicology at NCTR. Dr. Paule has played a major role in developing an automated system for monitoring multiple complex brain functions in nonhuman primates, children, and rodents. Utilization of similar or identical behavioral tasks across species serves to facilitate the interspecies extrapolation of exposure data and, thus, the risk assessment process. He is past President of the Behavioral Toxicology Society, the Neurobehavioral Teratology Society and the Neurotoxicology Specialty Section of the Society of Toxicology and Associate Editor for the journals NeuroToxicology and Neurotoxicology and Teratology. Dr. Paule has published over 225 research articles and 30 book chapters and holds Adjunct Professorships at the University of Arkansas for Medical Sciences in the Departments of Pharmacology and Toxicology and in Pediatrics. He is an elected Fellow in the Academy of Toxicological Sciences and in the International Behavioral Neuroscience Society.


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