Handbook of Pharmaceutical Analysis by HPLC

Erscheinungsjahr 2005
ISBN: 978-0-12-088547-3
Verlag: William Andrew Publishing

Buch, Englisch, 600 Seiten, Format (B × H): 165 mm x 240 mm, Gewicht: 1360 g

High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening).

Autoren/Hrsg.

Ahuja, Satinder

Dong, Michael

Fachgebiete

• Sozialwissenschaften Soziologie | Soziale Arbeit Soziologie Allgemein

Inhaltsverzeichnis

Key concepts of HPLC in pharmaceutical analysis
HPLC instrumentation: in pharmaceutical analysis: status, advances and trends
HPLC columns for pharmaceutical
Sample preparation for HPLC analysis of drug products
HPLC method development
Validation of HPLC methods in pharmaceutical analysis
Ion Chromatography
How to be more successful with HPLC analysis: practical aspects in HPLC operation
Regulatory considerations in HPLC anaysis
HPLC system calibration for GMP compliance
System validation: pre-installation, IQ, OQ and PQ
Assays and stability testing
Impurity evaluation
HPLC in dissolution testing
Cleaning validation using HPCL for analysis
LC/MS application in high throughput ADME screen
Chiral separations
Applications of LC/MS in pharmaceutical analysis
Application of LC-MMR in Pharmaceutical Analysis
Chromatography data systems (CDS) in the pharmaceutical laboratory; its history, advances and future direction
New developments in HPLC

Über Autor(innen)

Ahuja, Satinder
Satinder Ahuja is a leading expert on water quality improvement. He earned his PhD in analytical chemistry from the University of the Sciences in Philadelphia. He worked for Novartis Corp. in various leadership positions for over 25 years and taught as an adjunct professor at Pace University for over 10 years. As president of Ahuja Consulting, he advises on water quality issues relating to chemicals and pharmaceuticals. A member of the executive committee of the Rivers of the World Foundation (ROW), Dr. Ahuja has organized numerous global symposia on improving water quality, including presentations for the American Chemical Society and UNESCO. Dr. Ahuja has published numerous papers and more than 25 books. His latest books are Contaminants in Our Water (ACS, 2020); Evaluating Water Quality to Prevent Future Disasters (Elsevier, 2019); Advances in Water Purification Techniques (Elsevier, 2019); and Chemistry and Water (Elsevier, 2017).