Asymmetric Organocatalysis

New Strategies, Catalysts, and Opportunities
1. Auflage 2022
ISBN: 978-3-527-34907-4
Verlag: WILEY-VCH

Buch, Englisch, 768 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 1790 g

This timely book presents comprehensively the most important and latest developments in asymmetric organocatalysis. Focussing on new directions, reactions, and catalysts, it is an indispensable source for everyone working in this highly vivid research field.

Autoren/Hrsg.

Albrecht, Lukasz

Albrecht, Anna

Dell'Amico, Luca

Fachgebiete

• Naturwissenschaften Chemie Physikalische Chemie Chemische Reaktionen, Katalyse
• Technische Wissenschaften Technik Allgemein Nachhaltigkeit, Grüne Technologien
• Naturwissenschaften Chemie Chemie Allgemein
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

PART I. NEW CATALYSTS AND ACTIVATION STRATEGIES IN ASYMMETRIC ORGANOCATALYSIS
New Developments in Enantioselective Brønsted Acid Catalysis with Strong Hydrogen-Bond Donors
Organosuperbases - Moving beyond Classical Brønsted Base Catalysis
Asymmetric Phase-Transfer Catalysis - From Classical Applications to New Concepts
Asymmetric Ion-Pairing & H-Bonding Catalysis
Isothiourea Catalysis - New Opportunities for Asymmetric Synthesis
Halogen-Bonding Organocatalysis - New Opportunities for Asymmetric Synthesis
Merging Organocatalysis with Light - New Opportunities for Asymmetric Synthesis
Asymmetric Electrochemical Organocatalysis - New Opportunities for Synthesis
Synergistic Organo-Organocatalysis
Merging Organocatalysis with Metals - New Opportunities for Asymmetric Synthesis
Immobilized Organocatalysts for Enantioselective Continuous Flow Processes
Mechanochemistry and High-Pressure Techniques in Asymmetric Organocatalysis
Organocatalytic Reactions under Non-Traditional Conditions

PART II. NEW ORGANOCATALYTIC SYNTHETIC METHODOLOGIES
Merging Organocatalysis with Vinylogy - New Opportunities for Asymmetric Synthesis
Umpolung Organocatalytic Strategies - Beyond Classical Reactivity Patterns
Dearomative Organocatalytic Strategies
From Organocatalytic Cycloadditions to Asymmetric Higher-Order Cycloadditions
Asymmetric Organocatalysis - From a Process Development Perspective

PART III. MECHANISMS OF ORGANOCATALYTIC REACTIONS
Computational Studies - A Useful Tool in Elucidation of Mechanisms of Organocatalytic Reactions

A Tutorial on Kinetic-Assisted Mechanistic Analysis in Asymmetric Aminocatalysis

Mayr Linear Free Energy Relationship: A Powerful Tool for Understanding Aminocatalyzed Reactions

Über Autor(innen)

Lukasz Albrecht is full professor at the Institute of Organic Chemistry at Lodz University of Technology, Poland. He obtained his M.Sc. degree (2004), Ph.D. (2009) and habilitation (2015) from Lodz University of Technology. From 2009 - 2012 he stayed as a postdoctoral researcher with Prof. Karl Anker Jørgensen at the Center for Catalysis, Aarhus University (Denmark), working on new applications of asymmetric organocatalysis. Since 2013, he is a group leader at the Institute of Organic Chemistry at Lodz University of Technology. His research deals with the synthesis and utilization of chiral organic catalysts.

Anna Albrecht is associate professor at the Institute of General and Ecological Chemistry at Lodz University of Technology, Poland. She received her M.Sc. degree (2004) and Ph.D. (2009) from Lodz University of Technology. After a postdoctoral stay with Prof. Karl Anker Jørgensen at the Center for Catalysis, Aarhus University (Denmark), she returned to Lodz University of Technology. In 2020, she accomplished her habilitation working on the development of new decarboxylative synthetic strategies.

Luca Dell'Amico is associate professor at Padova University, Italy. He obtained his M.Sc. degree in medicinal chemistry (2011) and Ph.D. (2014) at Parma University, Italy. In 2013, he spent a ten-months research period with Prof. Karl Anker Jørgensen at the Center for Catalysis, Århus Univesity (Denmark). He was a Marie-Curie cofund fellow in the group of Prof. Paolo Melchiorre at ICIQ Tarragona (Spain) in 2014. His current research spans from the development of stereoselective photochemical processes to the investigation of novel organocatalytic methods using renewables.