Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 710 g
Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 710 g
ISBN: 978-0-443-23585-6
Verlag: Elsevier Science & Technology
Anti-Prostate Cancer Agents walks the readers through the anti-prostate cancer drug development pipeline from early discovery/design to clinical studies/applications. This book covers discovery/design, synthetic studies, preclinical evaluation, mechanism of action, structure-activity relationships, clinical studies/applications of anti-prostate cancer agents.
This book provides insight on how the design and discovery process of anti-prostate cancer agents have evolved from androgen deprivation therapy to current androgen receptor antagonists/degraders. So far, no book focusing on the topic has been published.
Weitere Infos & Material
1. Introduction: Overview of Prostate Cancer? ??? 2.?Why has one got prostate cancer? 3. Androgen Deprivation Therapy 4. Anti-prostate cancer agents interacting with topoisomerase 5. Microtubule-Stabilizing Compounds as Anti-Prostate Cancer Agents 6. Androgen/Androgen Receptor Signaling Pathway and Prostate Cancer? 7. Anti-Prostate Cancer Agents Suppressing Androgen Biosynthesis? 8. First Generation Nonsteroidal Androgen Receptor Antagonists? 9. Second Generation Nonsteroidal Androgen Receptor Antagonists 10. Anti-Prostate Cancer Agents Interacting with N-Terminal Domain of Androgen Receptor 11. Androgen Receptor Degraders as Anti-Prostate Cancer Agents 12. Radiotherapeutics for treatment of Prostate Cancer 13. Immunotherapy for Prostate Cancer 14. Radiosensitizer for prostate cancer? 15. Anti-Prostate Cancer Agents Targeting Prostate-Specific Membrane Antigen 16. Anti-Prostate Cancer Agents Targeting Poly(ADP-Ribose)Polymerase 17. Combined Anti-Prostate Cancer Agents 18. Future Directions?
