Managing BRCA Mutation Carriers

1. Auflage 2017
ISBN: 978-3-319-59197-1
Verlag: Springer International Publishing

Buch, Englisch, 242 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 5552 g

As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuable resource for a myriad of clinicians and healthcare personnel who interface with these patients. The text discusses the latest recommendations for genetic counseling and risk assessment, provides a framework for considering reducing risk in mutation carriers who do not present with a concomitant diagnosis of breast cancer, and finally elucidates the many considerations of managing a breast cancer patient with a BRCA mutation. The text presents a multidisciplinary approach gleaning insights from imaging, breast surgery, gynecology, plastic surgery, medical oncology, radiation oncology and psycho-oncology.

Managing BRCA Mutation Carriers will be a useful resource for physicians and healthcare providers from a myriad of disciplines who manage BRCA mutation carriers. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

B. Chagpar, Anees

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Onkologische Chirurgie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik

Inhaltsverzeichnis

Managing BRCA Mutation Carriers

Anees B. Chagpar

Contents

Preface

 Chapters

1 Risk Assessment for Breast Cancer

Anvy Nguyen, Jessica Cintolo-Gonzalez, Jennifer K. Plichta, and Kevin S. Hughes

 2 Genetic Evaluation for Women at Increased Risk

Karina L. Brierley, Claire L. Healy, and Erin W. Hofstatter

 3 Imaging Screening and Surveillance

Ellen Warner

 4 Risk Reducing Surgery for BRCA1/2 Genetic Mutation Carriers

Cristina O’Donoghue, Sonia Orcutt, Tuya Pal, and Christine Laronga

 5 Prophylactic Oophorectomy for Patients with Germline BRCA Mutations

Dario R. Roque and Don S. Dizon

 6 Pathology of BRCA Tumors

Julio A. Ibarra

 7 Surgical Management of Breast Cancer in BRCA Mutation Carriers

Patricia A. Cronin and Hiram S. Cody III

 8 Medical Management of Breast Cancer in BRCA Mutation Carriers

Soley Bayraktar and Banu K. Arun

 9 Radiation Oncology Considerations in the Management of Mutation Carriers with Breast Cancer

Meena S. Moran

 10 Fertility Preservation in BRCA Carriers: Special Considerations

Iris G. Insogna, Elizabeth S. Ginsburg and Ann H. Partridge

 11 Management of Male BRCA Mutation Carriers

Donna-Marie Manasseh, Ryland J. Gore and Patrick I. Borgen

 12 Psychosocial, Ethical and Legal Implications for Mutation Carriers

Jacquelyn M. Powers, Jessica M. Long and Willonie Mendonca

Über Autor(innen)

Anees B. Chagpar, MD, MSc, MPH, MA, MBA, FRCS(C), FACSAssociate Professor, Department of SurgeryDirector, The Breast Center -- Smilow Cancer Hospital at Yale-New HavenAssistant Director -- Global Oncology, Yale Comprehensive Cancer CenterYale University School of Medicine20 York Street, First floor Suite ANew Haven, CT 06510Phone:  [phone]