Chemistry and Biochemistry of B12

1. Auflage 1999
ISBN: 978-0-471-25390-7
Verlag: Wiley

Buch, Englisch, 944 Seiten, Format (B × H): 168 mm x 242 mm, Gewicht: 1442 g

Die erste Arbeit, die den Erkenntnisstand zum Vitamin B12 umfassend beschreibt! Angesprochen werden biologische, biochemische und chemische Problemkreise, beispielsweise zur Strukturchemie des Vitamins, zu Strukturbiologie und Reaktionsmechanismen der B12-abhängigen Enzyme und zur Rolle des Vitamins in der Ernährung und bei der Entstehung von Krankheiten. (09/99)

Autoren/Hrsg.

Banerjee, Ruma

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Chemie Chemie Allgemein
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)

Inhaltsverzeichnis

CHEMISTRY OF B_12.

B_12 History (H. Hogenkamp).

X-ray Crystallography of B_12 (B. Kräutler & C. Kratky).

X-Ray Absorption Spectorscopy of B_12: Structural Changes of Intermediate States (M. Chance).

Electronic Structure and Spectra of B_12: From Trans Effects to Protein Conformation I (J. Pratt).

Electronic Structure and Spectra of B_12: From Trans Effects to Protein Conformation II (J. Pratt).

EPR Spectroscopy of B_12-Dependent Enzymes (G. Gerfen).

NMR Spectroscopy of B_12 (K. Brown).

Vibrational Spectroscopy of B_12 and Related Compounds (L. Marzilli & S. Hirota).

Magnetic Field Dependence of Cobalamin Photochemistry and Enzymes (C. Grissom).

Stereospecificity of the Coenzyme B_12 Catalyzed Rearrangements and the Role of Negative Catalysis (J. Retey).

Modeling the Structure of Cobalt Corrins by Molecular Mechanics and Molecular Dynamics Methods (H. Marques).

B_12 Electrochemistry and Organometallic Electrochemical Synthesis (B. Kräutler).

BIOCHEMISTRY AND BIOLOGY OF B_12.

B_12 and Nutrition (S. Stabler).

Inborn Errors of Cobalamin Metabolism (D. Rosenblatt & W. Fenton).

Diagnostic and Therapeutic Analogs of Cobalamin (H. Hogenkamp, et al.).

Intrinsic Factor and Haptocorrin and Their Receptors (D. Alpers & G. Russell-Jones).

Transcobalamin II (S. Rothenberg, et al.).

Mammalian Receptors of Vitamin B_12-Binding Proteins (S. Moestrup & P. Verroust).

Cobalamin Transport in Bacteria (C. Bradbeer).

Biosynthesis of B_12 in the Aerobic Organism Pseudomonas denitrificans (A. Battersby & F. Leeper).

B_12 Biosynthesis: The Anaerobic Pathway (A. Scott, et al.).

Biosynthesis of the 5-6 Dimethylbenzimidazole Moiety of Cobalamin and of the Other Bases Found in Natural Corrinoids (P. Renz).

Regulation of Adenosylcobalamin Biosynthesis in Salmonella typhimurium (J. Semerena).

X-ray Crystallography of B_12 Enzymes: Methylmalonyl-CoA Mutase and Methionine Synthase (M. Ludwig & P. Evans).

The Acetogenic Corriniod Proteins (S. Ragsdale).

The Role of Corrinoids in Methanogenesis (K. Sauer & R. Thauer).

Methionine Synthase (R. Matthews).

Methylmalonyl-CoA Mutase (R. Banerjee & S. Chowdhury).

Ribonucleotide Reductases (M. Fontecave & E. Mulliez).

Glutamate Mutase and 2-Methyleneglutarate Mutase (W. Buckel, et al.).

Diol Dehydrase and Glycerol Dehydrase (T. Toraya).

Ethanolamine Ammonia-Lyase (V. Bandarian & G. Reed).

Anomutases (P. Frey).

Isobutyryl-CoA Mutase (K. Zerbe-Burkhardt, et al.).

Reductive Dehalogenases (G. Wohlfarth & G. Diekert).

Über Autor(innen)

Ruma Banerjee PhD, is the Vincent Massey Collegiate Professor of Biological Chemistry at the University of Michigan, Ann Arbor. She was the founding director of the Nebraska Redox Biology Center. Dr. Banerjee has published over one hundred articles and several book chapters, and edited The Chemistry and Biochemistry of Vitamin B-12.