Adenoviruses: Model and Vectors in Virus-Host Interactions

Immune System, Oncogenesis, Gene Therapy
1. Auflage. Softcover version of original hardcover Auflage 2004
ISBN: 978-3-642-05715-1
Verlag: Springer

Buch, Englisch, Band 273, 368 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 575 g

Reihe: Current Topics in Microbiology and Immunology

After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy.

Zielgruppe

Research

Autoren/Hrsg.

Böhm, Petra

Doerfler, Walter

Fachgebiete

• Naturwissenschaften Biowissenschaften Virologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gentherapie

Inhaltsverzeichnis

List of Contents.- 1 Immune System.- Evasion of the Immune System by Adenoviruses.- Immune Evasion by Adenovirus E3 Proteins: Exploitation of Intracellular Trafficking Pathways.- The Coxsackie-Adenovirus Receptor—A New Receptor in the Immunoglobulin Family Involved in Cell Adhesion.- Mechanisms of E3 Modulation of Immune and Inflammatory Responses.- 2 Oncogenesis.- Modulation of Oncogenic Transformation by the Human Adenovirus E1A C-Terminal Region.- Cell Transformation by Human Adenoviruses.- Tumorigenesis by Adenovirus Type 12 in Newborn Syrian Hamsters.- E1A-Based Determinants of Oncogenicity in Human Adenovirus Groups A and C.- 3 Gene Therapy.- Replicating Adenoviruses in Cancer Therapy.- Adenovirus Vectors: Biology, Design, and Production.