Buch, Englisch, Band 64, 350 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 773 g
Reihe: Progress in Drug Research
Buch, Englisch, Band 64, 350 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 773 g
Reihe: Progress in Drug Research
ISBN: 978-3-7643-7566-9
Verlag: Springer
This book brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identification of drug targets. It includes practical examples from the various "omic" sciences as well as theoretical examples of how integrated knowledge of these sciences can be applied to drug discovery. It is of interest to researchers in the pharmaceutical drug discovery environment, as well as those in the academic field with an interest in the functional application of the "omic" sciences.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
Weitere Infos & Material
Systems biology and its impact on anti-infective drug development.- Applications of transcriptional profiling in antibiotics discovery and development.- Chemical genetics: An evolving toolbox for target identification and lead optimization.- Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action.- Elucidating the mode-of-action of compounds from metabolite profiling studies.- A subsystems-based approach to the identification of drug targets in bacterial pathogens.- Metabolic control analysis to identify optimal drug targets.- The protein network as a tool for finding novel drug targets.- Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes.- Biological robustness in complex host-pathogen systems.- Toward whole cell modeling and simulation: Comprehensive functional genomics through the constraint-based approach.- Genomics of host-pathogen interactions.