Tight Junctions

2. Auflage 2001
ISBN: 978-0-8493-2383-6
Verlag: CRC Press

Buch, Englisch, 792 Seiten, Format (B × H): 166 mm x 241 mm, Gewicht: 1225 g

As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular biology, genetics and physiology. The field has advanced so fast and so far that it influences many areas of biology and now has practical implications for pharmacology of drug delivery and understanding a wide range of diseases altering epithelial permeability.

Zielgruppe

Researchers in Physiology, signal transduction, pathophysiology, pharmacology, genetics, immunology, cell biology

Autoren/Hrsg.

Cereijido, Marcelino

Anderson, James M.

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

Introduction: Evolution of Ideas on the Tight JunctionUltrastructure and Immuno-Labeling of the Tight JunctionIntercellular Junctions of InvertebratesTight Junction Permeability to Ions and WaterThe Relationship between Structure and Function of Tight JunctionsGeneral Themes in Cell-Cell Junctions and Cell AdhesionProtein Targeting Pathways and Sorting Signals in Epithelial CellsBiogenesis of Epithelial Polarity and Tight JunctionsOptical Methods for the Study of Tight JunctionsThe Claudin Family and OccludinThe Cytoplasmic Plaque Proteins of the Tight JunctionOrganization and Regulation of the Tight Junction by the Actin-Myosin CytoskeletonDevelopmental Assembly of the Tight JunctionTight Junctions and Cell Surface Lipid PolarityPhysiological Regulation of Tight Junction Permeability by Na+ Nutrient CotransportExtacellular Macromolecules Modulate Epethelial PermeabilityIntracellular Signaling in Classical and New Tight Junction FunctionsRegulation of Tight Junction Permeability in the Mammary GlandUnique Aspects of the Blood-Brain BarrierTeleost Chloride Cell Tight Junctions: Environmental salinity and Dynamic Stuctural ChangesTight Junctions and ProteasesClaudins Mediate Specific Paracellular Fluxes in VivoMicrobial Pathogens that Affect Tight JunctionsInteractions between Clostridium Perfringens Enterotoxin and Tight Junction ProteinsIschemia Induced Tight Junction Dysfunction in the KidneyTight Junctions in Intestinal InflammationTight Junctions in Liver DiseaseThe Tight Junctions in the TestisRelationship between Tight Junctions and Leukocyte TransmigrationOcular Tight Junctions in Health, Disease, and GlaucomaImplications of Transport via the Paracellular Pathway on drug DevelopmentPathological and Therapeutical Implications of Macromolecules Passage through the Tight JunctionFunctions of OSP/Claudin11-Containing Parallel Tight Junctions