Single-Molecule Fluorescence Spectroscopy of the Folding of a Repeat Protein

Softcover Nachdruck of the original 1. Auflage 2016
ISBN: 978-3-319-37236-5
Verlag: Springer

Buch, Englisch, 59 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 1299 g

Reihe: Springer Theses

In this thesis single-molecule fluorescence resonance energy transfer (FRET) spectroscopy was used to study the folding of a protein that belongs to the large and important family of repeat proteins. Cohen shows that the dynamics of the expanded conformations is likely to be very fast, suggesting a spring-like motion of the whole chain. The findings shed new light on the elasticity of structure in repeat proteins, which is related to their function in binding multiple and disparate partners. This concise research summary provides useful insights for students beginning a PhD in this or a related area, and researchers entering this field.

Zielgruppe

Research

Autoren/Hrsg.

Cohen, Sharona

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Chemie Analytische Chemie Magnetresonanz
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik

Inhaltsverzeichnis

Abstract.- Introduction.- Methods.- Results.- Discussion.- Summary and Future Plans.

Über Autor(innen)

Sharona Cohen is a trained physicist, specialized in optical systems, microscopy and spectroscopy. She acquired her PhD at the interdisciplinary chemical physics department at Weizmann Institute of Science.