Target Organ Toxicity, Volume II

1. Auflage 1986
ISBN: 978-0-8493-5776-3
Verlag: Taylor & Francis Inc

Buch, Englisch, 248 Seiten, Format (B × H): 216 mm x 279 mm, Gewicht: 726 g

This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Autoren/Hrsg.

Cohen

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

VOLUME II: Kidney as a Target Organ for Toxicity. Cardiac Toxic-ity. Lung as a Target Organ for Toxicity. Target Organ Toxic-ity: Male Reproductive System. Toxic Effects of the Female Repro-ductive System. Eye. Inner Ear. Endocrine Pancreas as a Target Organ for Toxicity. Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction. Organ Specificity in Tumor Initia-tion and Complete Carcinogenesis (including Species Variation). Index.