Target Organ Toxicity

Volume 2
1. Auflage 2020
ISBN: 978-0-367-25871-9
Verlag: Taylor & Francis

Buch, Englisch, 234 Seiten, Format (B × H): 210 mm x 280 mm, Gewicht: 590 g

Reihe: Routledge Revivals

First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.

Autoren/Hrsg.

Cohen, Gerald M.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Biowissenschaften
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
• Naturwissenschaften Chemie Chemie Allgemein Toxikologie, Gefahrstoffe, Sicherheit in der Chemie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Umweltmedizin, Arbeitsmedizin, Tropenmedizin, Sportmedizin Umweltmedizin

Inhaltsverzeichnis

1. The Kidney as a Target Organ for Toxicity 2. Cardiac Toxicity 3. The Lung as a Target Organ for Toxicity 4. Target Organ Toxicity: The Male Reproductive System 5. Toxic Effects on the Female Reproductive System 6. The Eye 7. The Inner Ear 8. The Endocrine Pancreas as a Target Organ for Toxicity 9. Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction 10. Organ Specificity in Tumor Initiation and Comple Carcinogenesis (Including Species Variation)

Über Autor(innen)

Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.