Buch, Englisch, 992 Seiten, Format (B × H): 219 mm x 276 mm
Buch, Englisch, 992 Seiten, Format (B × H): 219 mm x 276 mm
ISBN: 978-0-443-07271-0
Verlag: Churchill Livingstone
Since 1955, this landmark masterwork has been revered for its authoritative presentation of the entire state of scientific and clinical knowledge about multiple sclerosis. This new edition summarises the state of knowledge on this common neurological disease to mid-2005. No person who aspires to know about multiple sclerosis can do without this book! The state-of-the-art 4th Edition presents the most recent information on the genetics and epidemiology, clinical neurology, pathogenesis, and management of this common neurological disease. Amply illustrated and referenced and beautifully written, McAlpine's Multiple Sclerosis has been described as "A standard reference for multiple sclerosis researchers, embryonic 'MS-ologists' and hard-pressed clinical neurologists alike" (Brain, review of the last edition).
Zielgruppe
Neurologists, Libraries, MS patients, Pharmaceutical workers
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
SECTION ONE: THE STORY OF MULTIPLE SCLEROSIS
1. The story of multiple sclerosis
The evolving concept of multiple sclerosis
Naming and classifying the disease: 1868-1983
Clinical descriptions of multiple sclerosis: 1838-1981
Personal accounts of multiple sclerosis: 1824-1991
The social history of multiple sclerosis: 1945-1998
The pathogenesis and clinical anatomy of multiple sclerosis: 1849-1977
The laboratory science of multiple sclerosis: 1912-1981
Discovery of glia and remyelination: 1858-1988
The aetiology of multiple sclerosis: 1883-1976
Attitudes to the treatment of multiple sclerosis: 1841-1983
SECTION TWO: THE CAUSE AND COURSE OF MULTIPLE SCLEROSIS
2. The distribution of multiple sclerosis
The rationale for epidemiological studies in multiple sclerosis
Definitions and statistics in epidemiology
Strategies for epidemiological studies in multiple sclerosis
The geography of multiple sclerosis
Epidemics and clusters of multiple sclerosis
The environmental factor in multiple sclerosis
3. The genetics of multiple sclerosis:
Genetic analysis of multiple sclerosis
Methods of genetic analysis
Racial susceptibility
Sex differences in susceptibility
Familial multiple sclerosis
Candidate genes in multiple sclerosis
Systematic genome screening
Lessons from genetic studies of experimental allergic encephalomyelitis
Conclusions
4. The natural history of multiple sclerosis
Introduction
Definitions
Onset
Course
Inter-individual variability
Factors affecting the prognosis
General considerations
Environmental influences
Chapter 5: The aetiology of multiple sclerosis: an epitome
SECTION THREE: THE CLINICAL FEATURES AND DIAGNOSIS OF MULTIPLE SCLEROSIS
6. The symptoms and signs of multiple sclerosis.
Multiple sclerosis as a neurological illness
Initial symptoms
Symptoms and signs in the cou
