Manganese in Health and Disease

Erscheinungsjahr 2014
ISBN: 978-1-84973-943-6
Verlag: RSC Publishing

Buch, Englisch, 654 Seiten, Format (B × H): 152 mm x 251 mm, Gewicht: 1089 g

Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders.

The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases.

Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.

Autoren/Hrsg.

Costa, Lucio

Aschner, Michael

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Chemie Chemie Allgemein Toxikologie, Gefahrstoffe, Sicherheit in der Chemie
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie

Inhaltsverzeichnis

Manganese transport, trafficking and function in invertebrates;

Nutritional requirements for manganese;

Manganese: toxicokinetics, and toxicodynamics;

Health effects;

Neuro-epidemiologic studies of manganese exposure throughout the lifespan: implications for public health

Über Autor(innen)

Dr Michael Aschner is currently a Professor of Toxicology, Pharmacology and Pediatrics at Vanderbilt University Medical School. He is a world-known authority on the toxicology of manganese and of other metals. Also world-renowned for his contributions to the field, Dr Lucio Costa is a Professor of Toxicology at the University of Washington with over thirty years of experience in the area of neurotoxicology.