Buch, Englisch, 350 Seiten, Format (B × H): 156 mm x 234 mm
Reihe: Drug Discovery
Buch, Englisch, 350 Seiten, Format (B × H): 156 mm x 234 mm
Reihe: Drug Discovery
ISBN: 978-1-78262-434-9
Verlag: ROYAL SOCIETY OF CHEMISTRY
Firmly established as a model organism for biomedical research, zebrafish have also become increasingly important as an in vivo model for chemical biology and drug discovery. The first molecules found in zebrafish-based screens are now in human clinical trials. There is growing interest, both in the pharmaceutical industry and in academia, in the use of zebrafish as a platform for rapid in vivo disease modeling, drug discovery and toxicity screening.
This book introduces state-of-the-art zebrafish technologies to a general drug discovery audience. It highlights not only the latest disease models in various indication areas and their use for small-molecule screens, but also important updates on the latest technologies and tools important for zebrafish-based drug discovery and toxicity research. A unique feature of this book is the chapter summarizing the intellectual property situation for zebrafish technologies relevant for drug discovery.
This book will be a valuable resource for drug discovery scientists, companies considering implementing or accessing zebrafish drug discovery technologies, funding agencies, and investors. It is also sufficiently detailed for zebrafish researchers in both academia and industry.
Weitere Infos & Material
Introduction; chapters on tools e.g. genetic tools and imaging; chapters on disease models as bioassays for drug screening e.g. for cardiovascular diseases and inflammation; intellectual property; aquaculture
