Handbook of Glycomics

Erscheinungsjahr 2009
ISBN: 978-0-12-373600-0
Verlag: Elsevier Science

Buch, Englisch, 512 Seiten, Format (B × H): 192 mm x 275 mm, Gewicht: 1288 g

The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans.

Zielgruppe

biology researchers working in genomics, proteomics, systems biology, bioinformatics and novel therapeutics; glycobiology investigators; students in related areas

Autoren/Hrsg.

Cummings, Richard D

Pierce, J Michael

Fachgebiete

• Naturwissenschaften Biowissenschaften Kohlenhydrate

Inhaltsverzeichnis

Introduction to Glycomics

SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques

SECTION IV: Glycobioinformatics

8. Integration of Glycomics Knowledge and Data

9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures

10. European Glycomics Portal SECTION V: Glycomes

11. Glycomics of the Immune System

12. Mouse and Human

13. Drosophila

14. Malaria

15. Parasitic Worms

SECTION VI: Disease Glycomes

16. Cancer Glycomics

17. An Introduction to Human Disorders of Glycosylation

18. Summary