Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition

10 ed
ISBN: 978-1-259-58748-1
Verlag: McGraw-Hill Education

Buch, Englisch, 2512 Seiten, Format (B × H): 225 mm x 280 mm, Gewicht: 5150 g

Reihe: Pharmacy

The landmark text on how to achieve optimal patient outcomes through evidence-based medication therapy  Pharmacotherapy: A Pathophysiologic Approach is written to help readers advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Readers will find everything they need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest in evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers.  · A section on personalized pharmacotherapy appears in most sections· All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches are in full color to clearly distinguish treatment pathways· New drug monitoring tables have been added· Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that when available, include ratings of the level of evidence to support the key therapeutic approaches· Twenty-four online-only chapters are available at www.pharmacotherapyonline.com

Autoren/Hrsg.

DiPiro, Joseph T.

Talbert, Robert L.

Matzke, Gary R.

Yee, Gary

Wells, Barbara G.

Posey, L. Michael

Inhaltsverzeichnis

Contributors

Foreword

Foreword to the First Edition

Preface

Section 1 Foundation Issues

e1. Health Literacy and Medication Use

e2. Cultural Competency

e3. Medication Safety Principles and Practices

e4. Clinical Pharmacokinetics and Pharmacodynamics

e5. Pharmacogenetics

e6. Pediatrics

e7. Geriatrics

e8. Palliative Care

e9. Clinical Toxicology

e10. Clinical Management of Potential Bioterrorism-related Conditions

Section 2 Cardiovascular Disorders

e11. Cardiovascular Testing

12. Cardiac Arrest

13. Hypertension

14. Chronic Heart Failure

15. Acute Decompensated Heart Failure

16. Stable Ischemic Heart Disease

17. Acute Coronary Syndromes

18. The Arrhythmias

19. Venous Thromboembolism

20. Stroke

21. Dyslipidemia

e22. Peripheral Arterial Disease

23. Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock

24. Hypovolemic Shock

e25. Introduction to Pulmonary Function Testing

Section 3 Respiratory Disorders

26. Asthma

27. Chronic Obstructive Pulmonary Disease

28. Pulmonary Arterial Hypertension

29. Cystic Fibrosis

e30. Drug-Induced Pulmonary Diseases

Section 4 Gastrointestinal Disorders

e31. Evaluation of the Gastrointestinal Tract

32. Gastroesophageal Reflux Disease

33. Peptic Ulcer Disease and Related Disorders

34. Inflammatory Bowel Disease

35. Nausea and Vomiting

36. Diarrhea, Constipation, and Irritable Bowel Syndrome

37. Portal Hypertension and Cirrhosis

e38. Drug-Induced Liver Disease

39. Pancreatitis

40. Viral Hepatitis

41. Celiac Disease

Section 5 Renal Disorders

e42. Evaluation of Kidney Function

43. Acute Kidney Injury

44. Chronic Kidney Disease

45. Hemodialysis and Peritoneal Dialysis

46. Drug-Induced Kidney Disease

47. Glomerulonephritis

48. Drug Therapy Individualization for Patients with Chronic Kidney Disease

49. Disorders of Sodium and Water Homeostasis

50. Disorders of Calcium and Phosphorus Homeostasis

51. Disorders of Potassium and Magnesium Homeostasis

52. Acid–Base Disorders

Section 6 Neurologic Disorders

e53. Evaluation of Neurologic Illness

54. Alzheimer Disease

55. Multiple Sclerosis

56. Epilepsy

57. Status Epilepticus

58. Acute Management of the Brain Injury Patient

59. Parkinson Disease

60. Pain Management

61. Headache Disorders

Section 7 Psychiatric Disorders

e62. Assessment of Psychiatric Disorders

63. Attention Deficit/Hyperactivity Disorder

64. Eating Disorders

65. Substance-Related Disorders I: Overview and Depressants, Stimulants, and Hallucinogens

66. Substance-Related Disorders II: Alcohol, Nicotine, and Caffeine

67. Schizophrenia

68. Major Depressive Disorder

69. Bipolar Disorder

70. Anxiety Disorders: Generalized Anxiety, Panic, and Social Anxiety Disorders

71. Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder

72. Sleep–Wake Disorders

73. Disorders Associated with Intellectual Disabilities

Section 8 Endocrinologic Disorders

74. Diabetes Mellitus

75. Thyroid Disorders

76. Adrenal Gland Disorders

e77. Pituitary Gland Disorders

Section 9 Gynecologic and Obstetric Disorders

78. Pregnancy and Lactation: Therapeutic Considerations

79. Contraception

80. Menstruation-Related Disorders

81. Endometriosis

82. Hormone Therapy in Women

Section 10 Urologic Disorders

83. Erectile Dysfunction

84. Benign Prostatic Hyperplasia

85. Urinary Incontinence

Section 11 Immunologic Disorders

e86. Function and Evaluation of the Immune System

87. Systemic Lupus Erythematosus

e88. Drug Allergy

89. Solid-Organ Transplantation

Section 12 Rheumatologic Disorders

90. Osteoarthritis

91. Rheumatoid Arthritis

92. Osteoporosis and Osteomalacia

93. Gout and Hyperuricemia

Section 13 Ophthalmic and Otolaryngological Disorders

94. Glaucoma

95. Allergic Rhinitis

Section 14 Dermatologic Disorders

96. Acne Vulgaris

97. Psoriasis

98. Atopic Dermatitis

e99. Dermatologic Drug Reactions and Common Skin Conditions

Section 15 Hematologic Disorders

100. Anemias

101. Coagulation Disorders

102. Sickle Cell Disease

e103. Drug-Induced Hematologic Disorders

Section 16 Infectious Diseases

e104. Laboratory Tests to Direct Antimicrobial Pharmacotherapy

105. Antimicrobial Regimen Selection

106. Central Nervous System Infections

107. Lower Respiratory Tract Infections

108. Upper Respiratory Tract Infections

109. Influenza

110. Skin and Soft-Tissue Infections

111. Infective Endocarditis

112. Tuberculosis

113. Gastrointestinal Infections and Enterotoxigenic Poisonings

114. Intra-Abdominal Infections

e115. Parasitic Diseases

116. Urinary Tract Infections and Prostatitis

117. Sexually Transmitted Diseases

118. Bone and Joint Infections

119. Sepsis and Septic Shock

120. Superficial Fungal Infections

121. Invasive Fungal Infections

122. Infections in Immunocompromised Patients

123. Antimicrobial Prophylaxis in Surgery

e124. Travel Health

125. Vaccines and Immunoglobulins

126. Human Immunodeficiency Virus Infection

Section 17 Oncologic Disorders

127. Cancer Treatment and Chemotherapy

128. Breast Cancer

129. Lung Cancer

130. Colorectal Cancer

131. Prostate Cancer

132. Lymphomas

133. Ovarian Cancer

134. Acute Leukemias

135. Chronic Leukemias

136. Multiple Myeloma

e137. Myelodysplastic Syndromes

e138. Renal Cell Carcinoma

139. Melanoma

140. Hematopoietic Stem Cell Transplantation

Section 18 Nutritional Disorders

141. Assessment of Nutrition Status and Nutrition Requirements

142. Parenteral Nutrition

143. Enteral Nutrition

144. Obesity

Index

Über Autor(innen)

Posey, L. Michael
L. Michael Posey, RPh, is president of Pharmacy Editorial & News Services (PENS) in Athens, Georgia, and an editor for the APhA periodicals Journal of the American Pharmacists Association, Pharmacy Today, and APhA DrugInfoLine. He also assists with drug information content for APhAs cutting-edge Web site, www.pharmacist.com. During a career spanning two decades as a pharmacy communicator, Posey has served as editor of The Consultant Pharmacist and the American Journal of Hospital Pharmacy, and is an editor of the textbook Pharmacotherapy: A Pathophysiologic Approach.

Matzke, Gary R.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Talbert, Robert L.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Yee, Gary
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Wells, Barbara G.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

DiPiro, Joseph T.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Joseph DiPiro, PharmD, FCCP (Richmond VA)is professor and Archie O. McCalley Dean of the Virginia Commonwealth University School of Pharmacy. ,Robert Talbert, PharmD, FCCP, BCPS (San Antonio, TX) Retired Professor, University of Texas, Health Science Center.Gary Yee, PharmD, FCCP (Omaha, NB) Professor and Associate Dean for Academic Affairs, University of Nebraska, Medical Center.Barbara Wells, PharmD, FASHP, FCCP, BCPP (Jackson, MI) Former Dean and Professor, Executive Director of the Research Institute of Pharmaceutical Sciences, University of Mississippi School of Pharmacy.L. Michael Posey, BS Pharm (Athens, GA) former Editorial Director, American Pharmacists Association.Gary Matzke, (Richmond VA) VCU School of Pharmacy's associate dean for clinical research and public policy.