Morphological Diagnosis in Hematology

White Blood Cell Disorders – Cytomorphological Classification and Machine Learning Applications
Erscheinungsjahr 2027
ISBN: 978-3-032-42178-4
Verlag: Springer

Buch, Englisch, 410 Seiten, Format (B × H): 210 mm x 279 mm

This volume provides a comprehensive review of the morphological characteristics of leukocytes in benign and malignant disorders. Hundreds of figures from peripheral blood and bone marrow smears illustrating benign and malignant leukocyte disorders are presented, alongside an overview of machine learning models reported in the literature for the accurate morphological diagnosis of these conditions. This integrated approach supports hematologists, laboratory scientists, pathologists, and oncologists in achieving more accurate and timely diagnoses of both common and rare leukocyte disorders by combining traditional microscopic examination of blood and bone marrow smears with applications of machine learning and artificial intelligence.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Dorgalaleh, Akbar

Samadov, Anvarjon

Fachgebiete

• Mathematik | Informatik EDV | Informatik Angewandte Informatik Computeranwendungen in Wissenschaft & Technologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin
• Technische Wissenschaften Technik Allgemein Computeranwendungen in der Technik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie

Inhaltsverzeichnis

Normal White Blood Cell Morphology.- Neutrophilia and Toxic Granulation.- Neutropenia and Hyposegmentation.- Lymphocytosis and Atypical Lymphocytes.- Lymphopenia and Immunodeficiency.- Monocytosis and Monoblasts.- Eosinophilia and Eosinophil Toxicity.- Basophilia and Mast Cell Disorders.- Blast Cells and Immature Precursors.- Leukemoid Reaction vs Chronic Leukemia.- WBC Morphology in Sepsis and Critical Illness.- Malignant Lymphoproliferative Disorders.- Acute Lymphoblastic Leukemia (ALL).- Acute Myeloid Leukemia (AML).- Chronic Lymphocytic Leukemia (CLL).- Chronic Myeloid Leukemia (CML).- Hairy Cell Leukemia.- Leukemic Phase of Lymphoma (e.g., Mantle Cell, Burkitt).- Plasma cell neoplasms.

Über Autor(innen)

Akbar Dorgalaleh is a hematologist and scientific researcher specializing in thrombosis and hemostasis. He has (co-)authored more than 150 peer-reviewed publications and serves on the editorial boards of several international journals in the field of thrombosis and hemostasis. Dr. Dorgalaleh is the editor or co-editor of approximately ten published or forthcoming academic books, including (2nd edition, Springer, 2023). His academic work primarily focuses on inherited bleeding disorders, thrombophilia, and laboratory diagnostics in thrombosis and hemostasis, with particular emphasis on diagnostic strategies, laboratory evaluation, and advances in the understanding and management of these conditions.
Dr. Dorgalaleh is also a current or former member of several international scientific societies and working parties, including the Scientific and Standardization Committee (SSC) on Factor XIII and Fibrinogen of the International Society on Thrombosis and Haemostasis (ISTH), as well as the International Council for Standardization in Haematology (ICSH).

Anvarjon Samadov is a medical laboratory professional with extensive experience in clinical diagnostics and laboratory medicine. During his professional career, Mr. Samadov has developed substantial expertise in the practical and diagnostic aspects of laboratory medicine, particularly in hematology and coagulation testing. He is also the co-editor of the book (Springer, 2025).