Buch, Englisch, Band 23, 394 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 776 g
Reihe: Topics in Current Genetics
Buch, Englisch, Band 23, 394 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 776 g
Reihe: Topics in Current Genetics
ISBN: 978-94-007-4530-8
Verlag: Springer Netherlands
No other book published in this field of research
Presentation of all the innovative methodologies in genome engineering
From basic science to practical applications
Concerns a broad range of organisms (from bacteria to mammals)
From basic science to practical applications
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
- Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
Weitere Infos & Material
Preface.- Section 1: Site–directed integration of transgenes.- 1 Transgene site-specific integration : troubles and solutions.- 2 : Designing non-viral targetd integrating vectors for genome enginnering in vertebrates.- 3: Gene targeting and homologous recombination in Saccharomyces cerevisiae4: Eucaryotic homologous recombination in mammalian cells.- 5 Engineered Zinc Finger Nucleases for Targeted Genome Editing .- 6: Engineered meganucleases for genome engineering purposes.- Section3: Integration based on Site-specific recombination.- 7 : Cre/loxP, Flp/FRT systems and pluripotent stem cell lines.- 8 : Site-specific recombination using C31 Integrase.- 9 : Modified transposases used for site-directed insertion of transgenes.- 10 : Targeted Plasmid Integration into the Human Genome by Engineered Recombinases.- 11: Gene site-specific insertion in plants.- 12 Site-directed insertion of transgenes in Drosophila.- 13. Nuclease Mediated Targeted Genome Modification in Mammalian Cells.- 14: Bio-applications derived from site-directed genome modification technologies.
