Buch, Englisch, Band 6, 92 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 196 g
Reihe: Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik
Buch, Englisch, Band 6, 92 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 196 g
Reihe: Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik
ISBN: 978-3-642-87500-7
Verlag: Springer
Studies on microbial RNases began in 1924 when NOGUCHI found nucleic acid degrading enzymes in Takadiastase, a commercially prepared digest from Aspergillus oryzae. In 1935 OrANI reported the presence of enzymes degrading yeast RNA in fungi (Aspergillus sp. etc.). In 1948, MCCARTY studied the nuclease activity in 36 strains of group A hemolytic Streptococci and indicated the release of both RNase and DNase from Streptococcal cells during growth in culture media. As is well known, these nucleases (TILLETT et al., 1948) are applied in the treatment of inflammatory exudates. In 1952, MUGGLETON and WEBB found RNase in the culture medium of Actinomy ces (strain A), and they suggested that the ability of the medium to render killed Gram-positive cells Gram-negative may be due to the RNase. In the same year PARDEE and his colleagues (1952 a, b) found RNase activity in E. coli (strain B) in fected by bacteriophage T r, T3 etc. 2 KUNINAKA (1954) found ribonuclease in culture @trates of Aspergillus oryzae.
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Autoren/Hrsg.
Weitere Infos & Material
I. Introduction.- II. Classification of Enzymes Attacking RNA.- III. Distribution of RNases in Microorganisms.- Microorganisms of which RNA-Degrading Enzymes have been Investigated.- IV. Chemical Studies on Microbial RNases.- A. Introduction.- B. RNases of Aspergillus oryzae.- C. RNases of Streptomyces and Actinomyces.- D. RNases of Ustilago.- E. RNases of Neurospora crassa.- F. RNases of Azotobacter agilis (vinelandii).- G. RNase I of E. coli.- H. RNase of Aspergillus saitoi.- I. RNase of Bacillus subtilis.- J. Yeast RNase.- K. RNase II of E. coli.- L. RNase III of E. coli.- M. General Considerations.- V. Physiological Role of RNA-Degrading Enzymes in Microorganisms.- A. Introduction.- B. Role of Intracellular Enzymes with Special Reference to E. coli.- C. Role of Extracellular Enzymes.- VI. Concluding Remarks.- References.
