Advances in Microscale Electro- And Liquid Phase-Based Separation Techniques

Erscheinungsjahr 2026
ISBN: 978-0-443-34209-7
Verlag: Elsevier Science

Buch, Englisch, 900 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Advances in Microscale Electro- and Liquid Phase-Based Separation Techniques summarizes Microscale separation techniques characterized by fast, high resolution, and high efficiency with very reduced sample and solvent consumption. The book summarizes the existing body of knowledge, including hyphenated version to mass spectrometry (cLC-MS), capillary electrophoresis (CE), capillary zone electrophoresis (CZE and CZE-MS), micellar electrokinetic capillary chromatography (MEKC), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), capillary isotachophoresis (CITP), capillary electrochromatography (CEC), microfluidics, and microchips. It then demonstrates the applicability of these techniques to existing and future problems in the analysis of complex mixtures of biochemicals, pharmaceuticals, environmental, and natural products.

This book will be valuable to separation scientists, applications scientists, and technicians in industrial outlets, including those in pharmaceuticals, biomedicals, biotechnologies, and food and environmental industries. Students and professors who study separation techniques will also benefit greatly from the book's content.

Autoren/Hrsg.

El Rassi, Ziad

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Part I: Capillary Electrophoresis (CE)
1. Fundamentals of capillary electrophoresis
2. Instrumentation of capillary electromigration methods, Optical Detection
3. Recent trends in C4D for capillary and microchip electrophoresis and its applications
4. Capillary gel electrophoresis
5. Capillary Zone Electrophoresis
6. Surfactants and other Additives for Micellar Electrokinetic Capillary Chromatography
7. Capillary Isoelectric Focusing: theory, instrumentation, applications, and limitations
8. Capillary Isotachophoresis
9. Capillary Electrophoresis-Mass Spectrometry
10. Noise reduction techniques for capillary electrophoresis and electrochromatography
11. Capillary electrophoresis in the control of residues and contaminants in food
12. Capillary electrophoresis in pharmaceutical analysis
13. Is capillary electrophoresis well adapted for lipid separations?

Part II: Capillary Electrochromatography (CEC)
14. Basic principles and operational aspects of capillary electrochromatography
15. Theory and practice of capillary electrochromatography-mass spectrometry: opportunities and challenges
16. Applications of capillary electrochromatography

Part III: Capillary Liquid Chromatography
17. Fundamentals of capillary liquid chromatography-basic principles, advantages and limitations
18. Instrumentation of capillary liquid chromatography
19. Capillary liquid chromatography-mass spectrometry: a case study on glycans and glycoconjugates
20. Applications of capillary liquid chromatography

Part IV: Microfluidics and Microchips-Based Techniques
21. Microchip capillary electrophoresis and capillary electrochromatography
22. Fabrication methods for microchip capillary electrophoresis and capillary electrochromatography and their coupling to mass spectrometry
23. Instrumentation for microfluidic capillary liquid chromatography
24. Nanoscale electrophoresis of biomolecules

Über Autor(innen)

El Rassi, Ziad
Professor Ziad El Rassi earned M.S. and Ph.D. degrees in analytical chemistry from Claude-Bernard University, France, in 1974 and 1978. A visiting Assistant Professorship followed at Ecole Centrale de Lyon, France. He Joined the Chemical Engineering Department at Yale University in 1980. In 1988 he accepted an Assistant Professorship at Oklahoma State University, where he later became Full professor, followed by Regents Professor. El Rassi is a member of The Asia Pacific International Symposium on Microscale Separations, The International Symposium on Capillary Electroseparation Techniques (ITP), and The Latin-American Symposium on Biotechnology, Biomedical, Biopharmaceutical and Industrial Applications of Capillary Electrophoresis and Microchip Technology. He has served on editorial boards of several international journals and as the Chairman of three international symposia. He has received several research awards and his research has resulted in 200 research publications, two books, and 250 presentations, including 170 invited lectures around the world.