Landmark Papers in Pain

Seminal Papers in Pain with Expert Commentaries
1. Auflage 2018
ISBN: 978-0-19-883435-9
Verlag: Oxford University Press

Buch, Englisch, 334 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 617 g

Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice.

Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine.

Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.

Autoren/Hrsg.

Farquhar-Smith, Paul

Beaulieu, Pierre

Jaggar, Siân

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Geschichte der Medizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Schmerzmedizin & Schmerztherapie

Inhaltsverzeichnis

- Section 1: Historical

- 1: JAW (Tony) Wildsmith: Local anaesthetic substitutes for cocaine

- 2: Ben M. Thomas: Innovative concepts in pain management

- 3: Sebastian Brandner and Brigitta Brandner: Explaining reflex sympathetic dystrophy

- 4: Alain Eschalier and Christophe Mallet: The rediscovery of paracetamol

- 5: Fabrizio Benedetti: The pharmacology of placebos

- 6: Jean-Sébastien Walczak: Understanding the responsiveness of c-fibres

- 7: Tony Dickenson: A new theory of pain

- 8: Manon Choinière and Gabriella Pagé: Three determinants of pain

- 9: Guy Rousseau: Purinergic nerves: a new type of nerve

- 10: Jeffrey S. Mogil: Genetic differences in opiate receptors

- 11: Pierre Rainville: Endogenous opioids in placebo-induced analgesia

- 12: Éric Troncy: Ethical pain experimentation in conscious animals

- 13: Argyro Fassoulaki: Local anaesthetic creams

- 14: Cathy Price: The backpain revolution

- 15: Pierre Sirois and Pedro D'orléans-Juste: The mechanism of aspirin

- 16: Yasser Al Omran and Qasim Aziz: Mechanisms of visceral pain in IBS

- 17: Philippe Richebé and Cyril Rivat: The effects of morphine on the central nervous system

- 18: Joan Hester: Opiods in palliative care

- 19: Tony Dickenson: Endogenous opioids in the central nervous system

- 20: Craig W. Steven: Spinal opioid analgesia in the rat

- Section 2: Firsts

- 21: Paul Farquhar-Smith: The key role of NGF in inflammatory pain processing

- 22: Elizabeth J. Bradbury and Nicholas D. James: Mapping of neurotrophin receptors on adult sensory neurons

- 23: Stephen R. Humble: Plasticity in somatic receptive fields after nerve injury

- 24: Amanda Klein and Matthias Ringkamp: Peripheral neural mechanisms of cutaneous hyperalgesia and heat pain

- 25: Mary E. Abood and Thomas Gamage: The Cloning and Characterization of CB1

- 26: Mark F. Bird and David Lambert: Deorphanisation of ORL-1/LC132 by reverse pharmacology in two landmark studies

- 27: Istvan Nagy: The capsaicin receptor

- 28: Istvan Nagy: Vanilloid receptor 1 in inflammatory thermal hyperalgesia

- 29: Pierre Rainville: A signature of pain in the brain

- 30: John Schutzer-Weissmann: Cytokines as central to peripheral sensitisation and hyperalgesia

- 31: Claudia Sommer: Endogenous opioids mediate stress-induced analgesia

- 32: Ke Ren Ronald Dubner: The first crystal structure of an iGluR ligand-binding core

- 33: Andrea Hohmann: Control of pain initiation by endogenous cannabinoids

- 34: Julie Desroches: Peripheral Analgesia involves Cannabinoid Receptors

- 35: Marzia Malcangio: Glia: a new pain target

- 36: Bradley Kerr and Muhammad Saad Yousuf: The challenges of animal models of pain

- 37: Philippe Sarret: Mechanisms of bone cancer pain

- 38: Roger Knaggs: Molecular Structure of the Mu-Opioid Receptor

- 39: Serge Marchand: Milestone Effect of DNIC in our Understanding of Pain

- 40: Sheila Black: Original description of central sensitisation

- 41: Lesley Bromley: Molecular basis for Placebo effect

- Section 3: Science

- 42: Robert D. Searle: Early discussions on a mechanistic approach to pain

- 43: Alfredo Ribeiro and Da Silva Claire Magnussen: Plasticity: a key concept in pain

- 44: Enrique Collantes: The importance of descending modulatory pain systems

- 45: Helen Laycock: Nocebo and its importance in clinical practice

- 46: Pierre Beaulieu: Mechanisms of Action of Acetaminophen for Pain Treatment

- 47: Juergen Sandkuehler: Making the link from central sensitization to clinical pain

- Section 4: Clinical

- 48: Vicky Tidman: Proof of concept: epidural morphine

- 49: Mike Shipley: The Definition of Fibromyalgia

- 50: Suzanne Chapman: The advent of PCA for post operative analgesia

- 51: Matthew J. Allsop and Michael Bennett: Undertreatment of pain with metastatic cancer

- 52: Alison Bliss: Faces scales in paediatric pain assessment

- 53: Stephan Schug: Epidural block and phantom limb pain

- 54: Giovambattista Zeppetella: Clarifying the concept of Breakthrough pain

- Section 5: Mechanisms

- 55: Alison Bliss: Paediatric pain epidemiology

- 56: Peter Kamerman: Recognising the importance of HIV disease and pain

- 57: Andrew N. Davies: Fast acting fentanyl for breakthrough pain

- 58: Paul Farquhar-Smith: The additive analgesia of adrenaline in epidural blockade

- 59: Felicia Cox: What is the clinical relevance of the Likert scale for pain

- 60: Jane Quinlan: Post operative pain: assessing the standards

- 61: Kirsty Bannister: Opioid induced hyperalgesia

- 62: Naomi Scott: CRPS epidemiology

- 63: Paul Farquhar-Smith: Seminal paper on epidemiology of cancer pain

- 64: Arun Bhaskar: Endoscopic ultrasound guided coeliac plexus block

- Section 6: Neuropathic

- 65: Nicholas D. James and Elizabeth J. Bradbury: Autotomy: an early neuropathic pain model

- 66: Tudor Phillips: Risk factors for post amputation pain

- 67: Matthew Brown: Chronic constriction injury (CCI) model of neuropathic pain

- 68: Mick G. Serpell: Antineuropathic medication combination therapy

- 69: Rajesh Gupta: RCT evidence for gabapentin in post herpetic neuralgia

- 70: Turo J. Nurmikko: Identification of the target of gabapentinoid action in neuropathic pain

- 71: Matthew Brown: Recognition of the importance of Neuropathic pain epidemiology

- 72: Abdelghani Mowafak: Botox analgesia for neuropathic pain

- 73: Sibtain Anwar: DNIC and prediction of chronic post surgical pain

- 74: Richard M. Langford: Pregabalin in the reduction of chronic post knee surgery chronic pain

- 75: Toby Newton John: Multidisciplinary Cognitive Behavioural Treatment for Chronic Pain

- 76: Rakesh Jain: Disability in Chronic Low Back Pain

- Section 7: Psychosocial

- 77: Amanda Williams: The Understanding of Social Effects in Pain

- Section 8: Genetics

- 78: Bhagat Singh. Alban Latremoliere, and Michael Costigan: Congenital insensitivity to pain

- 79: Ingolf Cascorbi: Polymorphic CYP2D6 as the Responsible Enzyme of Activation

- 80: Matthew Hamilton: COMT genotypes in pain responses

- 81: Bradley J. Kerr: The link between NaV1.7 mutation and erythromelalgia

- 82: Fausto Morell-Ducos: COMT and morphine use in cancer pain

- 83: Roman Cregg and Biloshytsky Vadym: Pioneering use of gene therapy for pain

Über Autor(innen)

Dr Paul Farquhar-Smith, MA, MB, BChirFRCA, PhD, FFPMRCA, FFICM, is at present a Consultant in Pain Medicine and Anaesthesia at The Royal Marsden NHS Foundation Trust in London, UK. He specialises in pain in cancer patients and survivors (post-surgical chronic pain, chemotherapy induced neuropathy), and anaesthesia for breast and reconstructive surgery.

Dr Pierre Beaulieu is at present a Professor of Anesthesiology and Pharmacology at Université de Montréal in Canada. He specialises in the pharmacology and neurobiology of pain, the use of cannabinoids for treatment of pain, and in local anaesthetics

Dr Siân Jaggar is at present a Consultant in Anaesthesia at Royal Brompton & Harefield NHS Foundation Trust in London, UK. She specialises in adult and paediatric cardiothoracic anaesthesia and pain relief. She has a particular interest in education as a tool to enhance understanding between different working groups. She is the Royal College deputy regional advisor for the North West Thames region and the lead for less than full time trainees in this region.