Rapid Characterization of Microorganisms by Mass Spectrometry

1. Auflage 2012
ISBN: 978-0-8412-2612-8
Verlag: American Chemical Society

Buch, Englisch, Band 1065, 246 Seiten, Format (B × H): 159 mm x 228 mm, Gewicht: 474 g

Reihe: ACS Symposium Series

This book contains chapters from participants in a recent symposium, organized by the Division of Analytical Chemistry during the ACS National Meeting in Washington DC in August, 2009, as well as several other active researchers in the field. The book covers aspects of mass spectrometry (MS) applications for microorganism characterization in several fields: biodefense, clinical diagnostics, food safety, environmental monitoring, and chemotaxonomy/biosystematics. The
diverse list of contributors - from academia, government as well as industry present multi-faceted and broad perspectives on the subject to be presented.

Zielgruppe

Academics and professionals in related fields

Autoren/Hrsg.

Fenselau, Catherine

Demirev, Plamen

Fachgebiete

• Naturwissenschaften Chemie Analytische Chemie Massenspektrometrie, Spektroskopie, Spektrochemie

Inhaltsverzeichnis

1. Rapid Characterization of Microorganisms by Mass Spectrometry: An Overview

Catherine Fenselau and Plamen Demirev
2. Rapid Sample Preparation for Microorganism Analysis by Mass Spectrometry

Franco Basile
3. Discrimination of Fungi by MALDI-TOF Mass Spectrometry

Justin M. Hettick, Brett J. Green, Amanda D. Buskirk, James E. Slaven, Michael L. Kashon, and Donald H. Beezhold
4. Fungal Metabolites for Microorganism Classification by Mass Spectrometry

Vladimir Havlicek and Karel Lemr
5. Rapid Profiling of Recombinant Protein Expression from Crude Cell Cultures by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS)

Scott C. Russell
6. Detection, Differentiation and Subtyping of Botulinum Neurotoxins in Clinical Samples with Mass Spectrometry

John R. Barr, Suzanne R. Kalb, and James L. Pirkle
7. Rapid Identification of Food-Borne Pathogens by Top-Down Proteomics Using MALDI-TOF/TOF Mass Spectrometry

Clifton K. Fagerquist
8. Top-Down Protein Analysis and Phylogenetic Characterization of Unsequenced Bacteria

Nathan J. Edwards, Colin Wynne, Avantika Dhabaria, and Catherine Fenselau
9. Matrix Assisted Laser Desorption Ionization Ion Mobility Time-of-Flight Mass Spectrometry of Bacteria

Juaneka M. Hayes, Louis C. Anderson, J. Albert Schultz, Michael Ugarov, Thomas F. Egan, Ernest K. Lewis, Virginia Womack, Amina S. Woods, Shelley N. Jackson, Robert H. Hauge, Carter Kittrell, Steve Ripley, and
Kermit K. Murray

10. Single-Particle Aerosol Mass Spectrometry (SPAMS) for High-Throughput and Rapid Analysis of Biological Aerosols and Single Cells

Matthias Frank, Eric E. Gard, Herbert J. Tobias, Kristl L. Adams, Michael J. Bogan, Keith R. Coffee, George R. Farquar, David P. Fergenson, Sue I. Martin, Maurice Pitesky, Vincent J. Riot, Abneesh Srivastava, Paul T. Steele, and Audrey M. Williams
11. Rapid Detection and Identification of Aerosolized Biological Materials, Toxins, and Microorganisms by an AP-MALDI-MS-Based System

Berk Oktem, Appavu K. Sundaram, Jane Razumovskaya, Seshu K. Gudlavalleti, Thomas D. Saul, and Vladimir M. Doroshenko
12. MALDI Mass Spectrometry for Rapid Detection and Characterization of Biological Threats

Nathan A. Hagan, Jeffrey S. Lin, Miquel D. Antoine, Timothy J. Cornish, Rachel S. Quizon, Bernard F. Collins, Andrew B. Feldman, and Plamen A. Demirev
Editors' Biographies

Author Index

Subject Index

Über Autor(innen)

Demirev, Plamen
Plamen Demirev is a senior scientist at Johns Hopkins University.

Fenselau, Catherine
Catherine Fenselau is Professor at the University of Marylans.

Catherine Fenselau is Professor at the University of Marylans.

Plamen Demirev is a senior scientist at Johns Hopkins University.