Flavoproteins and Flavoenzymes

Erscheinungsjahr 2026
ISBN: 978-0-443-52012-9
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm

Flavoproteins and Flavoenzymes, Volume 738 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Kirisu2 and KiPaD: global analysis of rapid flavoprotein redox kinetics from stopped-flow multi, ilagros Mendina, A Generic First Approach to Dissecting Flavoenzyme Catalytic Cycles, Removing Covalent Constraints of Protein Loops and Lids by a Split-Gene Strategy, Designing Oxygen Reaction Sites in Flavoprotein Dehydrogenases, Converting Noncovalent Flavoproteins into Covalently Flavinylated Proteins, Complexities of Riboflavin Biosynthesis, Reactions of Riboflavin Catabolism, and much more.

Additional sections cover Ferredoxin-dependent thioredoxin reductase, Thermophilic Methylenetetrahydrofolate Reductases, Ion-Pumping NADH:Quinone Oxidoreductase, Loading E. coli Dihydroorotate Dehydrogenase with Coenzyme Q, and Single-Component Halogenases.

Autoren/Hrsg.

Weitere Mitwirkende

Christianson, David

Allen, Karen N.

Palfey, Bruce

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Physik Angewandte Physik Biophysik

Inhaltsverzeichnis

1. Photo-CIDNP as a Probe of Flavoprotein Structure
Stefan Weber
2. Kirisu2 and KiPaD: global analysis of rapid flavoprotein redox kinetics from stopped-flow multi-wavelength absorption spectroscopy data
Milagros Mendina
3. A Generic First Approach to Dissecting Flavoenzyme Catalytic Cycles
Bruce Palfey
4. Removing Covalent Constraints of Protein Loops and Lids by a Split-Gene Strategy
Steve Rokita
5. Designing Oxygen Reaction Sites in Flavoprotein Dehydrogenases
Karen Allen
6. Converting Noncovalent Flavoproteins into Covalently Flavinylated Proteins
Marco Fraaije
7. Complexities of Riboflavin Biosynthesis
Audrey L. Lamb
8. Reactions of Riboflavin Catabolism
Tadhg Begley
9. Ferredoxin-dependent thioredoxin reductase
Milagros Mendina
10. Thermophilic Methylenetetrahydrofolate Reductases
Markos Koutmos
11. Ion-Pumping NADH:Quinone Oxidoreductase
Oscar X. Juárez
12. Loading E. coli Dihydroorotate Dehydrogenase with Coenzyme Q
Bruce Palfey
13. Single-Component Halogenases
April Lukowski

Über Autor(innen)

Allen, Karen N.
Dr. Karen N. Allen works at the Department of Chemistry of the Boston University, the Metcalf Center for Science and Engineering

Palfey, Bruce
Dr. Bruce A. Palfey teaches at the Department of Biological Chemistry of the University of Michigan Medical School, U.S.A.

Christianson, David
After completing studies for the A.B., A.M., and Ph.D. degrees in chemistry at Harvard University, David W. Christianson joined the faculty of the University of Pennsylvania, where he is currently the Roy and Diana Vagelos Professor in Chemistry and Chemical Biology. At Penn, Christianson’s research focuses on the structural and chemical biology of the zinc-dependent histone deacetylases as well as enzymes of terpene biosynthesis. His research accomplishments have been recognized by several awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, a Guggenheim Fellowship, and the Elizabeth S. and Richard M. Cashin Fellowship from the Radcliffe Institute for Advanced Study at Harvard University. Christianson is also a dedicated classroom teacher, and his accomplishments in this regard have been recognized by the Lindback Award for Distinguished Teaching at Penn and a Rhodes Trust Inspirational Educator Award from Oxford University. Christianson has also held visiting professorships in the Department of Biochemistry at Cambridge University and the Department of Chemistry and Chemical Biology at Harvard University. Christianson has served with Prof. Anna Pyle as Co-Editor-in-Chief of Methods in Enzymology since 2015.