Buch, Englisch, 424 Seiten, GB, Format (B × H): 155 mm x 235 mm, Gewicht: 1770 g
Buch, Englisch, 424 Seiten, GB, Format (B × H): 155 mm x 235 mm, Gewicht: 1770 g
ISBN: 978-0-387-33418-9
Verlag: Springer US
For decades, bioinformatics textbooks have primarily served gene-hunters and biologists constructing family trees showing tidy lines of descent. Written to make the ‘new’ information-based bioinformatics intelligible to both the ‘bio’ and the ‘info’ audiences, this book identifies the types of information that genomes transmit, shows how competition between different types is resolved in the genomes of different organisms, and identifies the evolutionary forces involved. Early chapters relate the form of information with which we are most familiar, namely written texts, to the DNA text that is our genome. Providing a pathway for introducing historical aspects dating back to the nineteenth century.
Zielgruppe
Graduate
Autoren/Hrsg.
Weitere Infos & Material
Prologue.- Part 1: Memory-A Phenomenon of Arrangement.- Chargaff’s First Parity Rule.- Information Levels and Barriers.- Part 2: Chargaff’s Second Parity Rule.- Stems and Loops.- Chargaff’s Cluster Rule.- Part 3: Mutation and Speciation.- Species Survival and Arrival.- Chargaff’s GC Rule.- Part 4: Conflict with Genomes.- Conflict Resolution.- Exons and Introns.- Complexity.- Part 5: Conflict Between Genomes.- Sef/Not-Self?- The Crowded Cytosol.- Part 6: Sex and Error-Correction.- Rebooting the Genome.- The Fifth Letter.- Epilogue.- Appendix 1: What the Graph Says.- Appendix 2: Scoring Information Potential.- Appendix 3: No Line?- Acknowledgements.- References and Index.
