Foundation of Microfluidics Device Technology

Erscheinungsjahr 2026
ISBN: 978-0-443-43178-4
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm

Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale.

This volume presents the fundamental of microfluidics and microfluidics devices including computational design and fabrication, artificial intelligence and internet of things for microfluidics devices, materials, surface modifications and functionalization of microfluidics, fabrication of paper based microfluidics. Additional topics include microfluidics for generation of biomaterials, microfluidics for multi-omics analysis, lab-on-the-chip, microfluidics for 2D and 3D cell culture systms, microfluidics for drug and gene delivery, biomimetic models, and the economic considerations associated with microfluidics devices development. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

Autoren/Hrsg.

Weitere Mitwirkende

Singh, Vijai

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Physik Angewandte Physik Biophysik

Inhaltsverzeichnis

Preface
Vijai Singh
1. An introduction to microfluidics and devices
Vijai Singh, Khushal Khambhati and Vijai Singh
2. Computational design and modeling of microfluidics devices
Sameh Sherif, Ahmed M. R. FathEl-Bab, Yehya H. Ghallab and Yehea Ismail
3. Artificial intelligence and IoT for microfluidics devices
Alok Pandya
4. Fabrication techniques for design of microfluidics devices
Vijai Singh, Karan Murjani and Vijai Singh
5. Materials, surface modification and functionalization of microfluidic devices
Jawairia Khan
6. Fabrication of paper based microfluidics
Kapil Manoharan, Mona Vajpayee, Rashiku Mohammed, Ranamay Saha and Vishwesh Dutt Mishra
7. Microfluidics in biomaterials generation and formulation
Mustafeez Mujtaba Babar
8. Microfluidics for chemical and biological analysis
Adem Ozcelik and Sinan Gucluer
9. Recent progress in microfluidics for multi-omics data
Mugesh Sankaranarayanan, Sathya Narayanan Venkatesan, Uthesh Ragavan Rajangam, Akash Veeramani, Raaghul Gnanasekaran, Thendral Azhagan Hariraman, MD Fardeen Yusuf and Abhishek Ashok Nagargoje
10. Microfluidics devices for lab on chip growth
Pranab Kumar Mondal, Kaushal Agarwal, Dhruvkumar Wankawala and Giridhar Raveendar
11. Design of microfluidics devices for 2D/3D culture
Arpita Poddar
12. Paper-supported multilayer 3D cell culture
Bhushan Jayant Toley and Ankit Kumar
13. Microfluidics in precision of drug delivery
Mustafeez Mujtaba Babar
14. Microfluidics device for gene delivery
Indra Mani
15. Microfluidic Chips for Biomimetic Models
Samar Damiati, Safa A. Damiati and Laila A. Damiati
16. Social and economic aspects of microfluidics devices
Dinh Toi Chu Sr

Über Autor(innen)

Singh, Vijai
Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.