Buch, Englisch, 148 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 3731 g
Reihe: Springer Theses
Buch, Englisch, 148 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 3731 g
Reihe: Springer Theses
ISBN: 978-3-319-30236-2
Verlag: Springer International Publishing
The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
- Mathematik | Informatik EDV | Informatik Informatik Künstliche Intelligenz Neuronale Netzwerke
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
- Technische Wissenschaften Elektronik | Nachrichtentechnik Elektronik
- Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
- Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Biotechnologie: Mikrotechnologie, Nanobiotechnologie
Weitere Infos & Material
Introduction.- Dissociated Neuronal Networks Coupled to Micro-Electrode Arrays Devices.- In Vitro Neuronal Networks.- 3D Neuronal Networks: State of the Art.- 3D Neuronal Networks Coupled to MEAs.- Neuro-pharmacological Studies.- Discussion and Conclusion.- Data Analysis.
