Developments in Cancer Chemotherapy

1. Auflage 2020
ISBN: 978-0-367-24457-6
Verlag: Taylor & Francis Ltd

Buch, Englisch, 290 Seiten, Gewicht: 1102 g

Reihe: Routledge Revivals

First published in 1984: The broad scope of this book was intentionally designed as such to emphasize the enormous complexity, as well as the number of biological processes which can be exploited to derive new approaches for the treatment of cancer.

Autoren/Hrsg.

Glazer, Robert I.

Inhaltsverzeichnis

1. Pyrrolo [2,3-d] Pyrimidine Nucleosides
Paul S. Ritch and Robert I. Glazer
2. Purine Nucleoside Phosphorylase: A Target for Chemotherapy
Johanna D. Stoeckler
3. The Interaction of Methotrexate and 5-Fluoracil
Edwin C. Cadman
4. Inhibition of Cytidine Deaminase: Mechanism and Effects on the Metabolism of Antitumor Agents
Victor E. Marquez
5. Metabolic and Mechanistic Studies with Tiazofurin (ß-D-Ribofuranosylthiazole-4-Carboxamide)
Hiremagalur N. Jayaram and David G. Johns
6. Antimitotic Drugs and Tubulin-Nucleotide Interactions

Ernest Hamel
7. Cellular and Molecular Pharmacology of Sugar Amine-Modified Anthracyclines
James B. Johnston and Robert I. Glazer
8. Intercalator-Induced Protein-Associated DNA Strand Breaks in Mammalian Cells
Leonard A. Zwelling et al.
9. Growth Inhibitory Effects of Interferons and (2’,5’) Oligoadenylate and its Analogs
Miruna S. Chapekar and Robert I. Glazer
10. The 2’,5’-Oligoadenylates and Their Analogs: Biochemical Probes in the Treatment of Cancer and Virus-Related Diseases
Robert J. Suhadolnik
11. Induction of Differentiation of the Human Promyelocytic Cell Line HL-60 and Primary Cultures of Human Leukema Cells: A Model for Clinical Treatment
Hiromichi Hemmi and Theodore R. Breitman

Über Autor(innen)

Robert I. Glazer, Ph.D., Chief, Applied Pharmacology Section, Laboratory of Medicinal Chemistry and Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.