Cold-Adapted Enzymes

Biochemistry and Biotechnology
Erscheinungsjahr 2027
ISBN: 978-0-443-22366-2
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 191 mm x 235 mm

Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a cutting-edge investigation into the molecular mechanisms, structural dynamics, and regulatory pathways of enzymes adapted to cold environments.
Beyond classical microbiology, the book explores cold adaptation from psychrophilic bacteria and Antarctic fungi to microalgae, plants, and mammalian cell physiology. It provides biochemistry insights into carbohydrate (amylases, glucoamylases) and lipid metabolism, proteases, and redox enzymes, alongside the roles of molecular chaperones and prokaryotic proteomics. A key highlight is its focus on next-generation biotechnology, featuring AI-driven protein design, advanced computational modeling, and structural bioinformatics. Bridging foundational science with market reality, the volume explores applications from organic waste valorization to industrial biocatalysis, analyzing the global patent landscape and commercial players.
As the latest volume in the Foundations and Frontiers of Enzymology series, this book is an indispensable reference for researchers across biochemistry, biotechnology, structural biology, and microbiology.

Autoren/Hrsg.

Gomez-Casati, Diego

Wayllace, Natael Maximiliano

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Structural and functional properties of cold-adapted enzymes.
2. Structural features of cold-adapted enzymes
3. Stability of proteins in cold environments
4. Molecular mechanisms of cold-adapted enzymes
5. Enzyme evolution in cold environments
6. Diversity of cold-adapted enzymes
7. Molecular adaptations of psychrophilic enzymes
8. Bacterial cold-adapted enzymes
9. Cold-adapted enzymes from Marine bacterium
10. Cold-adapted enzymes in carbohydrate metabolism
11. Cold-adapted proteases
12. Cold-adapted metalloproteases
13. Cold-adapted enzymes in lipid metabolism
14. Cold-adapted amylases
15. Cold-adapted redox enzymes
16. Cold-adapted dehydrogenases
17. Cold-adapted enzymes from Antarctic organisms
18. Biotechnological applications of cold-adapted enzymes
19. Recombinant expression of cold-adapted enzymes
20. Protein engineering of cold-adapted enzymes
21. Computational approaches to study the cold adaptation of enzymes
22. Computational engineering of cold-adapted enzymes
23. Biodiversity of physcrophilic bacteria
24. New cold-adapted enzymes and their applications

Über Autor(innen)

Gomez-Casati, Diego
Dr. Diego Gomez-Casati is a senior academic and research scientist at the Centre for Photosynthetic and Biochemical Studies and Professor of Chemical Biology at the National University of Rosario, Argentina. He is PI of the Plant and Algae Molecular Biology and Biotechnology Laboratory and Vice-Director. Dr. Gomez Casati has a PhD in Biochemistry from the University of Buenos Aires. He was a visiting scientist at California State University, Fullerton, USA, Laboratoire Microbiologie Cellulaire et Moleculaire et Pathogenicite, Centre National de la Recherche Scientifique (CNRS), Université Bordeaux-2 and Pontificia Universidad Católica de Chile. He was also Professor of Plant Biotechnology at the National University of San Martín (UNSAM). Dr. Gomez-Casati’s research interests include the study of the structure, function and regulation of polysaccharide metabolism enzymes and their biotechnological applications. He has published over 85 research papers, reviews and book chapters, most related to the biochemical characterization of enzymes of energy metabolism.

Wayllace, Natael Maximiliano
Dr. Natael Maximiliano Wayllace is a Postdoctoral Researcher at the Center for Photosynthetic and Biochemical Studies (CEFOBI-CONICET), National University of Rosario, Argentina. He obtained his PhD in Biological Sciences in 2024, where he discovered and characterized novel microbial enzymes, with a particular focus on extremophilic systems, including cold-adapted and thermostable glucoamylases. His research combines biochemical and kinetic characterization with computational modeling to investigate enzyme adaptation mechanisms and structure–function relationships. Dr. Wayllace has authored several peer-reviewed publications on microbial enzymes, including studies on the structural and functional properties of cold-active glucoamylases. He has extensive university teaching experience and has supervised undergraduate students in biotechnology. His expertise in cold-adapted enzymes, enzymology, and protein engineering, is complemented by his academic contributions as reviewer and thesis examiner.