The Gut Microbiome in Health and Disease

1. Auflage 2018
ISBN: 978-3-319-90544-0
Verlag: Springer

Buch, Englisch, 356 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1165 g

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Zielgruppe

Graduate

Autoren/Hrsg.

Haller, Dirk

Fachgebiete

• Naturwissenschaften Biowissenschaften Bakteriologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Medizinische Mikrobiologie & Virologie

Inhaltsverzeichnis

- Intestinal Microbiome in Health and Disease: Introduction. - Composition and Function of the Gut Microbiome. - Microbiome and Early Life. - Molecular Microbiome Analysis. - Evolutionary Perspectives on the Human Gut Microbiome. - Microbiome and Diet. - Microbiome and Gut Immunity: The Epithelium. - Microbiome and Gut Immunity: Innate Immune Cells. - Microbiome and Gut Immunity: T Cells. - Microbiome and Gut Immunity: B Cells. - Microbiome and Diseases: Inflammatory Bowel Diseases. - Microbiome and Diseases: Allergy. - Microbiome and Diseases: Graft-Versus-Host Disease. - Microbiome and Diseases: Pathogen Infection. - Microbiome and Diseases: Colorectal Cancer. - Microbiome and Diseases: Metabolic Disorders. - Microbiome and Diseases: Hepatic Disorders. - Microbiome and Diseases: Neurological Disorders. - Clinical Implementation of High-Throughput Sequencing. - Fecal Transplantation.- Gnotobiology.

Über Autor(innen)

Dr. Dirk Haller is Full Professor for Nutrition and Immunology and Director of the Institute for Food & Health at the Technical University of Munich. He received his academic training at the University of Hohenheim, graduating in Nutrition Science and Food Technology, and completed his PhD in Microbiology and Immunology. Following periods of post-doctorial research in Switzerland (Nestlé Research Center) and USA (University of North Carolina at Chapel Hill), he received carreer and science awards from the German Research Foundation (DFG)  and the German Society of Medical Microbiology (DGHM). He pioneered the concept of microbe-host interactions and substantially contributed to the understanding of chronic inflammatory disorders in the gut.