Parathyroid Hormone-Related Protein

Normal Physiology and Its Role in Cancer
1. Auflage 2020
ISBN: 978-0-367-22983-2
Verlag: Taylor & Francis

Buch, Englisch, 224 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 571 g

Reihe: Routledge Revivals

First Published in 1992, since its discovery, a substantial body of information has been amassed concerning the functions of parathyroid hormone-related protein (PTHrP) in normal and malignant states. This book provides a state-of-the-art discussion of the major aspects of PTHrP biology and pathophysiology, in addition to presenting a historical perspective and discussions on the molecular biology of PTHrP, its mechanism of action, bioassays and radioimmunoassays, and its role in normal physiology. The book will be a primary resource for physicians interested in the clinical aspects of paraneoplastic hypercalcemia and mineral metabolic disorders. It will also serve as a primary resource for basic scientists in skeletal and renal physiology, tumor biology, and hormone action.

Autoren/Hrsg.

Halloran, Bernard P.

Nissenson, Robert A.

Weitere Mitwirkende

Goltzman, David

Broadus, Arthur E.

Stewart, Andrew F.

Strewler, Gordon J.

Martin, T. John

Hendy, Geoffrey N.

Thiede, Mark A.

Soifer, Neil E.

Rodda, Christine P.

Caple, Ivan W.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie

Inhaltsverzeichnis

1. Identification of the Parathyroid Hormone-Related Peptide. 2. Molecular Biology of Parathyroid Hormone-Like Peptide. 3. Expression and Regulation of the Parathyroid Hormone-Related Protein Gene in Tumors and Normal Tissues. 4. Measurement of PTH-Related Protein and the Role of PTH-Related Protein in Malignancy-Associated Hypercalcemia. 5. Molecular Mechanism of Action of PTHrP. 6. Role of PTHrP Fetal and Neonatal Physiology. Index