Precision Medicine

1. Auflage 2020
ISBN: 978-1-0716-0906-4
Verlag: Springer US

Buch, Englisch, Band 2204, 226 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 460 g

Reihe: Methods in Molecular Biology

This book serves to introduce the technologies and applications of precision medicine. Beginning with a section on emerging experimental and bioinformatics technologies, the collection continues with chapters covering cancer studies, cardiovascular diseases, COPD and systemic lupus erythematosus, as well as the latest engineering and surgical developments in precision medicine. As a volume in the highly successful Methods in Molecular Biology series, this book presents key information from experts in the field. 
Authoritative and cutting-edge, Precision Medicine covers perspectives of precision medicine from basic research to clinical surgeries, from cancer to cardiovascular disease, from sequencing technology to big data analysis in the hope of broadening the horizons for researchers, engineers, and clinicians and accelerating the interdisciplinary precision medicine research and applications.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Huang, Tao

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Naturwissenschaften Biowissenschaften Biowissenschaften
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Naturwissenschaften Biowissenschaften Angewandte Biologie Bioinformatik

Inhaltsverzeichnis

Part I: Emerging Experimental and Bioinformatics Technologies

1. T Cell Receptor Repertoire Sequencing

            Huixin Lin, Yonggang Peng, Xiangbin Chen, Yuebin Liang, Geng Tian, and Jialiang Yang

2. Nanopore Sequencing and Its Clinical Applications

            Xue Sun, Lei Song, Wenjuan Yang, Lili Zhang, Meng Liu, Xiaoshuang Li, Geng Tian, and Weiwei Wang

3. The Clinical Significance of Microsatellite Instability in Precision Treatment

            Zhenyu Huang, Xiaojian Chen, Chenying Liu, and Long Cui

4. Applications of Network Analysis in Biomedicine

            Steven Wang and Tao Huang

Part II: Precision Medicine of Cancers

5. Diagnosis and Treatment of Breast Cancer in the Precision Medicine Era

            Jing Yan, Zhuan Liu, Shengfang Du, Jing Li, Li Ma, and Linjing Li

6. Application and Analysis of Biomedical Imaging Technology in Early Diagnosis of Breast Cancer

            Lin Chen, Nan Jiang, and Yuxiang Wu

7. Recent Advances in DNA Repair Pathway and Its Application in Personalized Care of Metastatic Castration-Resistant Prostate Cancer (mCRPC)

            Chenyang Xu, Shanhua Mao, and Haowen Jiang

8. Methylation in Lung Cancer: A Brief Review

            Chang Gu and Chang Chen

9. Epstein–Barr Virus DNA in Nasopharyngeal Carcinoma: A Brief Review

            Fen Xue and Xiayun He

10. A Review on Cancer of Unknown Primary Origin: The Role of Molecular Biomarkers in the Identification Unknown Primary Origin

            Na Yan, Yanxiang Zhang, Xuejie Guo, Dawei Yuan, Gen Tian, and Jialiang Yang

Part III: Precision Medicine of Cardiovascular Diseases

11. DNA Methylation in Atrial Fibrillation and Its Potential Role in Precision Medicine

            Mengwei Lv, Wen Ge, Zhi Li, Chao Wang, and Yangyang Zhang

12. PCSK9 Inhibition and Atherosclerosis: Current Therapeutic Option and Prospection

            Pratik Pandey, Cuimei Zhao, and Ban Liu

13. Precise Drug Sequential Therapy Can Improve the Cardioversion Rate of Atrial Fibrillation with Valvular Disease after Radiofrequency Ablation

            Tao Li and Yongjun Qian

14. Precision Medicine and Dilated Cardiomyopathy

            Xiang Li and Wenyan Zhu

15. Research Progress in Pathogenesis of Total Anomalous Pulmonary Venous Connection

            Xin Shi, Yanan Lu, and Kun Sun

Part IV: Precision Medicine of Other Complex Diseases

16. Airway Inflammation Biomarker for Precise Management of Neutrophil-Predominant COPD

            Xue Liang, Ting Liu, Zhiming Zhang, and Ziyu Yu

17. Genome Variation and Precision Medicine in Systemic Lupus Erythematosus

            Ru Yang, Yaqi Hu, and Lin Bo

Part V: Engineering and Surgical Developments in Precision Medicine

18. Precision Medicine in Tissue Engineering on Bone

            Bingkun Zhao, Qian Peng, Rong Zhou, Haixia Liu, Shengcai Qi, and Raorao Wang

19. Progress of Clinical Application for Ex Vivo Lung Perfusion (EVLP) in Lung Transplantation

            Chang Gu, Xufeng Pan, and Jianxin Shi