Buch, Englisch, 400 Seiten, Format (B × H): 156 mm x 234 mm
Buch, Englisch, 400 Seiten, Format (B × H): 156 mm x 234 mm
Reihe: Chapman & Hall/CRC Biostatistics Series
ISBN: 978-1-4822-1806-0
Verlag: Taylor & Francis
This book focuses on innovative designs that are easy to understand, easy to implement and conceptually intuitive. The author includes methods he recently developed plus ideas and concepts that could greatly improve the efficiency of the drug development process. The book targets a broad audience, ranging from statistics professionals to clinicians who have little statistical training. It covers practical designs for early phase trials and therefore should be attractive to practitioners in the early stage of drug development.
Autoren/Hrsg.
Weitere Infos & Material
Introduction to Bayes. Phase I Dose-Finding Designs. Phase I Designs Based on Toxicity. Phase I/II Designs Based on Joint Efficacy/Toxicity. Adaptive Dose Insertion. Phase II Trial Designs. Optimal and Minimax Two-Stage Designs. Bayesian Adaptive Designs. Seamless Designs. Phase I-II Seamless Designs. Phase II-III Seamless Designs. Some Practical Considerations. Borrowing Strength in Phase I Trials. the Necessity of Phases. Adaptive Learning to Speed Up Phase III. Change of Models for Early Phase Designs.
