The Dynamic Genome and Mental Health

The Role of Genes and Environments in Youth Development
1. Auflage 2011
ISBN: 978-0-19-973796-3
Verlag: Oxford University Press

Buch, Englisch, 480 Seiten, Format (B × H): 231 mm x 155 mm, Gewicht: 680 g

While it is widely accepted that we are products of our genes and environment, misconceptions about the power of genes to control our destiny continue to dominate our discourse. This volume contains the latest theories and evidence supporting the highly dynamic inter-relation between genes and environments as they influence the development, mental health, and substance use of adolescents. Written by researchers who are leading the way toward this new understanding, this text provides overviews and analysis of this emerging field. The chapters discuss the latest approaches to gene-environment relations, including gene-environment interaction, gene-environment correlation, epigenetics, and environmental regulation of gene expression. The application of these concepts to the prevention of adolescent mental health conditions, such as drug use, conduct disorder, depression, and schizophrenia, is included. Controversies in the implications of these approaches are also discussed.

The chapters are written in accessible language and will relevant to anyone interested in the mental health and development of adolescents, including researchers and practitioners in behavioral, social and medical fields. A final chapter by the editors assesses the implications of these new approaches for future mental health research and policy.

Zielgruppe

Researchers and practitioners in behavioral psychology, social psychology, and other medical fields related to mental health

Autoren/Hrsg.

Kendler, Kenneth S.

Jaffee, Sara

Romer, Daniel

Fachgebiete

• Sozialwissenschaften Psychologie Allgemeine Psychologie Entwicklungspsychologie
• Sozialwissenschaften Psychologie Psychotherapie / Klinische Psychologie
• Sozialwissenschaften Psychologie Allgemeine Psychologie Sozialpsychologie
• Sozialwissenschaften Pädagogik Pädagogik Pädagogische Psychologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie

Inhaltsverzeichnis

- Part I: Overviews of Research on Gene-Environment Interplay

- 1.: A Conceptual Overview of Gene-Environment Interaction and Correlation in a Developmental Context

- Kenneth S. Kendler

- 2.: Gene-Environment Interactions

- Rudolf Uher

- 3.: Improving Environmental Markers in Gene-Environment Research: Insights from Life Course Sociology

- Michael J. Shanahan and Shawn Bauldry

- 4.: Genotype-Environment Correlations: Definitions, Methods of Measurement, and Implications for Research on Adolescent Psychopathology

- Sara Jaffee

- 5.: The Social Dynamics of the Expression of Genes for Cognitive Ability

- William T. Dickens, Eric Turkheimer, and Christopher Beam

- 6.: Family Relationship Influences on Development: What Can We Learn from Genetic Research?

- Briana Horwitz, Kristine Marceau, and Jenae M. Neiderhiser

- 7.: Epigenetic Effects on Gene Function and their Role in Mediating Gene-Environment Interactions

- Jonathan Mill

- 8.: Integrating Knowledge of Genetic and Environmental Pathways to Complete the Developmental Map

- M. Maria Glymour, Wim Velling, and Ezra Susser

- 9.: Socio-Environmental Effects on Gene Expression

- Steve W. Cole

- Part II: Dynamics of Genes and Environments in Behavioral and Mental Health Conditions: Anxiety and Depression

- 10.:. The Interplay between Genes and Environment in Anxiety and Depression

- Thalia C. Eley

- 11.: Adolescence and Risk for Anxiety and Depression: Insights from Human Imaging to Mouse Genetics

- BJ Casey, Erika Ruberry, and Victoria Libby

- 12.: Genetic and Environmental Predictors of Depression

- Francheska Perepletchikova and Joan Kaufman

- Substance Use and Other Externalizing Behaviors

- 13.: Genes, Environment, and Adolescent Smoking: Implications for Prevention

- Janet Audrain-McGovern and Kenneth P. Tercyak

- 14.: The Dynamic Nature of Genetic and Environmental Influences on Alcohol Use and Dependence

- Danielle M. Dick

- 15.: The Importance of Understanding Gene-Environment Correlations in the Development of Antisocial Behavior

- Brian M. D'Onofrio, Paul J. Rathouz, and Benjamin B. Lahey

- 16.: Peer group deviance, conduct disorder and alcohol intake

- Kenneth S. Kendler

- Schizophrenia and Stress

- 17.: Stress Hormones, Genes, and Neuronal Signaling In Adolescence: The Perfect Storm for Vulnerability to Psychosis

- Elaine F. Walker, Hanan D. Trotman, Joy Brasfield, Michelle Esterberg, and Molly Larsen

- 18.: The Role of Stress and its Interaction with Genetic Predisposition in Schizophrenia

- Valeria Mondelli, Marta Di Forti, Carmine M. Pariante, and Robin M. Murray

- Part III: Implications for the Future

- 19.: Conclusions and Implications for the Future

- Kenneth S. Kendler, Sara Jaffee, and Daniel Romer

Über Autor(innen)

Kenneth S. Kendler, MD, is Professor of Psychiatry and Human and Molecular Genetics at Virginia Commonwealth University and Director of the Virginia Institute for Psychiatric and Behavioral Genetics

Sarah Jaffee, PhD, is a Developmental Psychopathologist at Kings College, London

Daniel Romer, PhD, is Dan Romer is director of the Adolescent Communication Institute (ACI) of the Annenberg Public Policy Center at the University of Pennsylvania