Diabetes and Alzheimer's Disease

Erscheinungsjahr 2025
ISBN: 978-0-443-40559-4
Verlag: Elsevier Inc

Buch, Englisch, 404 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 693 g

Diabetes and Alzheimer's Disease: Mechanisms and Management delves into the complex relationship between diabetes and Alzheimer’s disease. The book examines how these conditions intersect and influence each other, providing insights into their pathophysiological and epidemiological aspects. Readers will gain a thorough understanding of metabolic interactions, molecular signaling, and various factors that regulate the confluence of these diseases. Written by experts, this comprehensive guide is essential for researchers, academicians, scientists, and graduate students in biomedical and pharmaceutical sciences. In addition to exploring the mechanisms, the book discusses theranostics and strategies to manage both conditions.

It includes sections on drug repositioning, dietary modifications, and the impact of metabolic dysfunction on neurological disorders.

Autoren/Hrsg.

Kumar, Awanish

Anju, T. R.

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Introduction to Confluence of Diabetes and Alzheimer's Disease
2. Epidemiology related to Diabetes and Alzheimer's Disease
3. Pathophysiology of Diabetes and Alzheimer's Disease
4. Metabolic Relationship and Crosstalk in Diabetes and Alzheimer's Disease
5. Insulin Signaling in Diabetes and Alzheimer's Disease
6. Epigenetic Insight of Alzheimer's Disease and Diabetes
7. Inflammation in Alzheimer's Disease and Diabetes
8. Possible impact of Co-occurrence of Alzheimer's Disease and Diabetes
9. Impact of Oxidative Stress on Diabetes and Alzheimer's Disease
10. Cognitive Dysfunction: Link between Diabetes and Alzheimer's Disease
11. Theronostics in Alzheimer's Disease and Diabetes
12. Drug Repositioning Strategies of Anti-diabetic Drugs for Alzheimer's Disease
13. Nutritional Aspect and Management of Alzheimer's Disease and Diabetes

Über Autor(innen)

Kumar, Awanish
Dr. Awanish Kumar is an Associate Professor of the Department of Biotechnology at the National Institute of Technology, Raipur, Chhattisgarh, India. He has more than 13 years of research experience. He received his PhD in molecular parasitology from the CSIR-Central Drug Research Institute, Lucknow, India, and Jawaharlal Nehru University, Delhi, India, and completed his postdoctoral studies at McGill University, Montreal, Canada. His research interests are infection biology, drug targeting, and drug discovery.

Anju, T. R.
Dr. T.R. Anju is currently an Assistant Professor in biotechnology at Newman College, Kerala, India, and Secretary of Society for Biotechnologists, India. She completed her Master’s degree in biotechnology at Gulbarga University, Karnataka, India and doctoral degree at the Centre for Neuroscience, Cochin University of Science and Technology, Kochi, India. She completed her postdoctoral research on a 5-year project funded by the Department of Biotechnology to study the long-term effects of neonatal hypoglycemia. She has published 48 research papers in SCI journals, 27 book chapters, and edited 7 books and is the recipient of the Kerala State Young Scientist Award 2012 by the Kerala State Council for Science, Technology and Environment, and various other awards. Her research is focused on molecular signaling and neurotransmitter receptor functions in the brain under neonatal stress and various disease conditions like diabetes and epilepsy. Currently, her research team is working on nanotechnology and phytoconstituent-based interventions for biomedical applications.