Chemoresistance in Glioblastoma

Understanding and Management
Erscheinungsjahr 2025
ISBN: 978-0-443-33910-3
Verlag: Elsevier Science

Buch, Englisch, 420 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 450 g

Chemoresistance in Glioblastoma: Understanding and Management gives clear insights into the detailed characteristic aspects of glioblastoma disease and the different therapeutic targets that are employed in reducing resistance to chemotherapeutic agents. The book delves deep into the root causes of multidrug resistance and the quest for novel molecular targets among growth factors, receptors, signal transduction proteins, microRNAs, transcription factors, proto-oncogenes, and tumor suppressor genes. In addition, it gives insights on the pathological and molecular features of glioblastoma and the role of cancer stem cells in the resistance to chemo and immunotherapy.

While designed as a comprehensive guide, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within chemoresistance.

Autoren/Hrsg.

Kumar, Dileep

Sharma, Rohit

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Molecular Mechanisms Underlying Treatment Resistance in Glioblastoma and current therapies
2. A comprehensive outline of glioblastoma and molecular chemotherapy
3. Brain tumors: diagnosis and treatment
4. Unveiling the Therapeutic Tapestry: mRNA and RNA Vaccines in the Nexus of Glioblastoma's Pathological and Molecular Landscae.
5. Cell Cycle Arrest and Apoptosis in Glioblastoma
6. Cancer stem cells in resisting chemotherapy and the recurrence of glioblastoma multiforme
7. Variability in Natural Invasion of Tumor Cells Patterns in Human Glioblastoma
8. Epigenome in Gliomas: Novel Targets for Therapy
9. Adaptation of Mitochondria in Drug Resistance of Cancer: Frequency, Mechanisms, and Control
10. Immunotherapy resistant glioblastoma.
11. Dynamics of glioblastoma chemotherapy in blood-brain barrier
12. Epigenetic Modifications and Therapies of Gliomas: A Precision Medicine Perspectives

Über Autor(innen)

Kumar, Dileep
Dileep Kumar received his B. Pharm from Manipal College of Pharmaceutical Sciences, Manipal University, and M. Pharm from S.G.S.I.T.S Indore, Madhya Pradesh. He has several patents to his credit. He was awarded a Junior Research fellowship by National Medicinal Plant Board (NMPB) New Delhi, Senior Research Fellowship from University Grants Commission (UGC), Teaching Assistantship, and institute Post-Doctoral fellowship from IIT (BHU) Varanasi. At present, he is teaching as an assistant professor at Poona College of pharmacy, Bharti Vidyapeeth University Pune. He has published many papers and patents. He is Guest editor of several Prestigious journals. At present he is visiting professor in the department of entomology and Comprehensive Cancer Center in university of California Davis