Wound Microenvironment Responsive Smart Dressing for Effective Healing

Erscheinungsjahr 2027
ISBN: 978-0-443-52681-7
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 191 mm x 235 mm

Wound Microenvironment Responsive Smart Dressing for Effective Healing presents a cutting-edge scientific exploration of phytoconstituent-based smart wound dressings engineered to accelerate and improve tissue repair. Bridging the therapeutic wisdom of traditional herbal medicine with advanced biomaterials, nanotechnology, polymer science, and bioengineering, this volume highlights how natural bioactive compounds can be transformed into clinically viable wound therapies. The book provides an integrated understanding of the molecular and cellular mechanisms governing wound healing, and demonstrates how stimuli-responsive delivery platforms—sensitive to pH, temperature, enzymes, ROS, or glucose—can enable precise, controlled release of phytochemicals directly at the wound site. These innovative systems overcome limitations of conventional formulations, such as instability, poor solubility, low bioavailability, and lack of targeted action. With contributions spanning smart hydrogels, nanocarriers, microneedles, 3D/4D printing, and AI-assisted wound monitoring, this multidisciplinary reference offers both foundational principles and translational guidance. Case studies and globally inclusive perspectives ensure broad relevance for researchers, clinicians, and formulation scientists working toward next-generation wound management solutions.

Autoren/Hrsg.

Kumar, Mohit

Singh, Thakur Gurjeet

Bhatia, Amit

Kumar, Akshay

Kumar, Devesh

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Introduction to Wound Healing
2. Evolution of Wound Dressings: From Conventional to Smart Systems and the Clinical Challenges
3. Principles and Design of Stimuli-Responsive Smart Wound Dressings
4. Phytoconstituent-Based Smart and Stimuli-Responsive Formulations for Wound Healing
5. Nanotechnology enabled targeted Wound Dressings
6. Microneedle-assisted Wound Dressing
7. Advanced Materials: Hydrogels, Aerogels, and Conductive Networks
8. 3D and 4D Printing in Smart Dressings
9. Preclinical Evaluation, Biocompatibility, Regulatory and Translational Challenges of Smart Dressing 10. Future Artificial Intelligence-based Smart Drssing for Wound Healing

Über Autor(innen)

Kumar, Akshay
Akshay Kumar is a research scholar at the University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh, with a strong passion for learning, exploration, and innovation in pharmaceutical research. Since January 2024, he has been engaged in analytical method development and validation, degradation chemistry, and advanced chromatographic and spectroscopic techniques, including LC–MS. He has also served as a Junior Research Fellow and Project Associate on IPCA Foundation projects, contributing to formulation development, characterization, and liposome-based drug delivery systems. Akshay holds an M.Pharmacy degree (2021–2023) and has developed expertise in analytical sciences, Good Laboratory Practice (GLP), and data analysis. His research contributions include publications on derivative UV-spectrophotometric assay methods, nanoparticle spectroscopic analysis, and characterization of alkaline hydrolytic degradation products using UPLC-PDA and UPLC-ESI-QTOF-MS techniques.

Kumar, Devesh
Devesh Kumar is a Research Scholar and Junior Research Fellow at Chitkara College of Pharmacy, Chitkara University, Punjab, India, dedicated to advancing pharmaceutical research with sincerity, curiosity, and scientific integrity. He was recently awarded First Prize in the Best Master’s Thesis in 3 Minutes competition at an International Conference, a recognition that reflects his hard work, perseverance, and commitment during his M.Pharm journey.

Bhatia, Amit
Dr. Amit Bhatia is an Associate Professor in the Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab. He’s been working in drug delivery, formulation development and strategies. Dr. Bhatia was part of the core team at the university for development and technology transfer of 3 novel drug delivery/carriers-based products in the market. He has 3 patent/design granted and 4 patents/design published to his credit. He has guided 2 PhD and 24 PG students & currently supervising 4 PG and 5 PhD. Scholars. He has published over 40 research and review articles in prestigious journals, primarily in areas of drug delivery, polymers, clinical and translational research. He is involved in various research projects and consultancy supported by government and industries. He is a recipient of Young Nanotechnologist award by NIPER, Mohali.

Singh, Thakur Gurjeet
Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.

Kumar, Mohit
Mohit Kumar is an Assistant Professor, Chitkara College of Pharmacy, Chitkara University, Punjab, India. Dr. Kumar has dedicated his expertise to addressing the global concern of burn-related wound infections, affecting approximately 11 million people globally every year. His prolific academic journey includes the authorship of 9 book chapters and 50+ publications, published in high-impact science journals. His outstanding contributions have earned him prestigious accolades such as the Young Researcher Award at an international conference in Pondicherry (India 2023) and the Best Paper Award at ICONICA 2020 India. He is recognized by the Central Library of Medicine Foundation of Argentina for a groundbreaking paper focused on perfumes. He is also recipient of international travel support from SERB, Govt. of India to attend international conference held at Italy.