Uhmwpe Biomaterials Handbook

Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices
4th Auflage
ISBN: 978-0-443-29919-3
Verlag: Elsevier Science

Buch, Englisch, 850 Seiten, Format (B × H): 216 mm x 276 mm

UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices, Fourth Edition describes the science, development, properties, and application of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This book is the comprehensive reference for information on this advanced material, covering both introductory topics and the most advanced developments. This thoroughly revised new (4th) edition is divided into four distinct sections, deftly guiding the reader through the foundations, bearings, biomaterials, and specific development aspects of UHMWPE in total joint replacement. New to this edition are five chapters on a range of topics, including the latest in development and characterization of chemically crosslinked HXLPE for joint replacement, and assessment of the clinical performance of antioxidant technologies for stabilizing HXLPE. Use of UHMWPE liners for dual mobility total hip replacement is discussed, as well as applications in the hand and wrist. Written and edited by the top experts in the field of UHMWPE, this is the only state-of-the-art reference for professionals, researchers, and clinicians working with this material.

Autoren/Hrsg.

Kurtz, Steven M.

Fachgebiete

• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Polymerwerkstoffe
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Technologie der Kunststoffe und Polymere
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Keramik, Glas, Sonstige Werkstoffe
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

PART I: Polyethylene Biomaterials Foundations
1. A Primer on Polyethylene Biomaterials
2. Processing of UHMWPE
3. Sterilization and Packaging of Polyethylene Biomaterials

PART II: UHMWPE and Alternative Bearings in Orthopedics
4. The Origins of UHMWPE in Orthopedics
5. Clinical Performance of Conventional UHMWPE in Hip Replacements
6. Clinical Performance of HXLPEs in Hip Replacement
7. Dual Mobility Total Hip Replacement
8. Hard-on-Hard Bearing Materials in Contemporary Hip Arthroplasty
9. Origins and Adaptations of UHMWPE for Knee Replacements
10. Clinical Performance of Conventional UHMWPE in Knee Replacements
11. Clinical Performance of Alternative Bearings in Knee Replacement
12. Clinical Performance of Anti-Oxidant HXLPE in Total Joint Replacement
13. Applications of UHMWPE in Shoulder Replacements
14. Applications of UHMWPE in Elbow Replacements
15. Applications of UHMWPE in the Hand and Wrist
16. Applications of UHMWPE in Ankle Replacements
17. Applications of UHMWPE in Total Disc Replacement
18. Applications of HXLPE for Total Joint Replacement of the Spine

PART III: UHMWPE Biomaterials
19. Highly Crosslinked and Melt-Stabilized UHMWPE
20. Chemically Crosslinked HXLPE
21. Highly Crosslinked and Annealed UHMWPE
22. UHMWPE Blended with Vitamin E
23. Highly Crosslinked UHMWPE Doped with Vitamin E
24. Alternative Antioxidants to Vitamin E in UHMWPE
25. MPC Grafted UHMWPE
26. Carbon-Reinforced UHMWPE Biomaterials
27. UHMWPE Homocomposites and Fibers
28. UHMWPE-Hyaluronan Polymer Networks
29. High-Pressure Crystallized UHMWPE
30. Compendium of UHMWPE Biomaterials

PART IV: Scientific, Biologic, and Engineering Aspects of UHMWPE
31. Mechanisms of Crosslinking, Oxidative Degradation, and Antioxidant Stabilization of UHMWPE
32. In Vivo Degradation of UHMWPE
33. Biologic Reactions to UHMWPE Wear Particles
34. Characterization of UHMWPE
35. Tribological Assessment of UHMWPE in Pin-on-Disc Simulators
36. Tribological Assessment of UHMWPE in the Hip
37. Tribological Assessment of UHMWPE in the Knee
38. Characterization of UHMWPE Wear Particles
39. Clinical Surveillance of UHMWPE Using Radiographic Methods
40. Electron Spin Resonance and Macroradical Detection in UHMWPE
41. Fatigue and Fracture Behavior of UHMWPE
42. Notch Sensitivity of UHMWPE
43. Development and Application of the Small Punch Test to UHMWPE
44. Computer Modeling and Simulation of UHMWPE
45. Micro- and Nanoindentation Testing of UHMWPE
46. MicroCT Analysis of Wear and Damage in UHMWPE

Über Autor(innen)

Kurtz, Steven M.
Dr. Kurtz has been researching ultra-high molecular weight polyehtylene(UHMWPE) for use in orthopedics for over 10 years. He has published dozens of papers and several book chapters related to UHMWPE used in joint replacement. He has pioneered the development of new test methods for the material in orthopedics. Dr. Kurtz has authored national and international standards for medical upgrade UHMWPE.

As a principle engineer at Exponent, an international engineering and scientific consulting company, his research on UHMWPE is supported by several major orthopedic manufacturers. He has funding from the National Institutes for Health to stdy UHMWPE changes after implanatation in the body, as well as to develop new computer-based tools to predict the performance of new UHMWPE materials.

Dr. Kurtz is the Director of an orthopedic implant retrieval program in Philadelphia which is affiliated with Drexel University and Thomas Jefferson University. He teaches classes on the performance of orthopedic polymers (including UHMWPE) at Drexel, Temple, and Princeton Universities.