Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

1. Auflage. Softcover version of original hardcover Auflage 2000
ISBN: 978-3-642-08649-6
Verlag: Springer

Buch, Englisch, 140 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 248 g

Reihe: Research and Perspectives in Alzheimer's Disease

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

Zielgruppe

Research

Autoren/Hrsg.

Lee, V.M.-Y.

Trojanowski, J.Q.

Buee, L.

Christen, Y.

Fachgebiete

• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tierphysiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Neurochirurgie

Inhaltsverzeichnis

The Role of ?-Synuclein in Parkinson’s Disease: A Biophysical Analogy to A? and Alzheimer’s Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.