Atomic Force Microscopy for Nanoscale Biophysics

From Single Molecules to Living Cells
Erscheinungsjahr 2023
ISBN: 978-0-323-95360-3
Verlag: Elsevier Science

Buch, Englisch, 336 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 630 g

Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

Autoren/Hrsg.

Li, Mi

Fachgebiete

• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Physik Quantenphysik Atom- und Molekülphysik
• Naturwissenschaften Physik Elektromagnetismus Mikroskopie, Spektroskopie
• Naturwissenschaften Biowissenschaften Biowissenschaften Biologische Mikroskopie
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik

Inhaltsverzeichnis

1. Fundamentals and methods of AFM for biophysics 2. Imaging and force detection of DNA by AFM 3. High-resolution imaging and force spectroscopy of membrane proteins by AFM 4. Characterizing the nanostructures and properties of hydrogels by AFM 5. Detecting the behaviours of single virus by AFM 6. Nanoscale imaging and force probing of single microbial cells by AFM 7. Investigating the structures and mechanics of single animal cells by AFM 8. Combining AFM with complementary techniques: Hybrid AFM for biophysics 9. Conclusion and future perspectives

Über Autor(innen)

Li, Mi
Mi Li PhD is a Full Professor at Shenyang Institute of Automation Chinese Academy of Sciences, Shenyang, China. Mi Li received the Ph.D. degree in 2015 from Shenyang Institute of Automation (SIA) Chinese Academy of Sciences, Shenyang, China, after which he continues academic career at SIA until now. Since 2009, Mi Li has been engaged in the studies of atomic force microscopy (AFM) and its biomedical applications ranging from molecules and organelles to cells as well as hydrogels, to reveal the role of micro/nanoscale biophysical cues in regulating life activities. Mi Li has conducted long-term visitor studies at The Ohio State University, Columbus, USA and ETH Zurich, Switzerland, respectively for academic research regarding AFM. Mi Li has won the National Natural Science Foundation of China for Excellent Young Scholars (2019), the IEEE Senior Member (2020), the Outstanding Doctoral Dissertation Award of Chinese Academy of Sciences (2016) and the Springer Theses (2018).